CHRNA10 anticorps (Middle Region)

N° du produit ABIN951514

Détail du produit anti-CHRNA10 anticorps

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Épitope: AA 186-214, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CHRNA10.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 186-214 amino acids from the Central region of human CHRNA10

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CHRNA10

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Autre désignation: CHRNA10 (CHRNA10 Produits)

Synonymes: anticorps si:dkey-24p1.3, anticorps ALPHA 10 nAChR, anticorps cholinergic receptor, nicotinic, alpha polypeptide 10, anticorps cholinergic receptor nicotinic alpha 10 subunit, anticorps cholinergic receptor, nicotinic, alpha 10a, anticorps neuronal acetylcholine receptor subunit alpha-10, anticorps cholinergic receptor, nicotinic, alpha 10 (neuronal), anticorps Chrna10, anticorps CHRNA10, anticorps chrna10a, anticorps LOC100344381

Sujet: CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.Synonyms: NACHR alpha-10, NACHRA10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10

Poids moléculaire: 49705 Da

ID gène: 57053

NCBI Accession: NP_065135

Pathways: Sensory Perception of Sound, Synaptic Membrane