anti-Souris APP anticorps pour Western Blotting

Recommended APP Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Amyloid beta (A4) Precursor Protein (APP) Anticorps
  • AAA
  • ABETA
  • ABPP
  • AD1
  • APPI
  • CTFgamma
  • CVAP
  • PN-II
  • PN2
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • APP-like
  • APPL
  • Abeta
  • BcDNA:GH04413
  • CG7727
  • Dmel\\CG7727
  • EG:65F1.5
  • appl
  • Abpp
  • Adap
  • Ag
  • Cvap
  • E030013M08Rik
  • betaApp
  • app
  • wu:fj34d10
  • wu:fk65e12
  • zgc:85740
  • amyloid beta precursor protein
  • amyloid beta (A4) precursor protein
  • beta amyloid protein precursor-like
  • amyloid beta (A4) precursor protein a
  • amyloid beta precursor protein L homeolog
  • APP
  • app
  • Appl
  • App
  • appa
  • app.L
Épitope
AA 672-713, C-Term
105
102
70
39
37
32
31
19
17
15
15
14
14
13
12
10
9
7
7
7
7
6
6
6
5
5
5
5
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
931
383
361
40
27
22
19
18
15
13
12
10
7
7
4
4
4
3
2
2
1
Hôte
Lapin
646
261
51
7
2
Clonalité
Polyclonal
Conjugué
Cet anticorp APP est non-conjugé
51
43
41
17
16
14
14
14
13
13
13
13
13
13
13
8
8
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
668
405
293
159
158
122
82
57
40
36
17
15
15
10
8
3
3
2
1
1
1
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N° du produit ABIN3043787
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
3.2286417 ABIN2777738 WB Rabbit Middle Region Connectez-vous pour afficher Polyclonal 1
3.2286417 ABIN2777739 IHC WB Rabbit Middle Region Connectez-vous pour afficher Polyclonal 1
3.2286417 ABIN2787850 WB Rabbit C-Term Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN2779739 IHC WB Rabbit C-Term Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN2855011 ICC IF IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN2465038 ELISA WB Goat N-Term Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN358841 EIA WB Rabbit Ig Fraction N-Term Connectez-vous pour afficher Polyclonal 5
3.2286417 ABIN1449275 WB Mouse IgG1 AA 18-38 Connectez-vous pour afficher 3-00E-009 3
3.2286417 ABIN2464967 ELISA WB Goat N-Term Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN4281249 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Connectez-vous pour afficher Polyclonal 1
3.2286417 ABIN1871049 IF IHC WB Rabbit IgG Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN1532190 IF IHC ELISA WB Rabbit IgG AA 711-760 Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN1531173 IF IHC ELISA WB Rabbit IgG AA 711-760, pThr743 Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN317496 EIA IHC (p) WB Mouse IgG2b AA 18-289 Connectez-vous pour afficher J4H9 0
3.2286417 ABIN2451920 IC IF IHC WB Rabbit C-Term, AA 671-695 Connectez-vous pour afficher Polyclonal 5
3.2286417 ABIN1869978 IHC WB Rabbit IgG pThr743 Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN2451919 IC IF WB Rabbit N-Term, AA 18-38 Connectez-vous pour afficher Polyclonal 4
3.2286417 ABIN1869980 WB Rabbit IgG pThr668 Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN1871051 IHC WB Rabbit IgG Connectez-vous pour afficher Polyclonal 0
3.2286417 ABIN1858064 ICC IHC WB Rabbit IgG AA 672-770 Connectez-vous pour afficher Polyclonal 0

General

Antigène Amyloid beta (A4) Precursor Protein (APP) Anticorps
Épitope AA 672-713, C-Term
(105), (102), (70), (39), (37), (32), (31), (19), (17), (15), (15), (14), (14), (13), (12), (10), (9), (7), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(931), (383), (361), (40), (27), (22), (19), (18), (15), (13), (12), (10), (7), (7), (4), (4), (4), (3), (2), (2), (1)
Hôte Lapin
(646), (261), (51), (7), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp APP est non-conjugé
(51), (43), (41), (17), (16), (14), (14), (14), (13), (13), (13), (13), (13), (13), (13), (8), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(668), (405), (293), (159), (158), (122), (82), (57), (40), (36), (17), (15), (15), (10), (8), (3), (3), (2), (1), (1), (1)
Pubmed 4 références disponible
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Détail du produit anti-APP anticorps

Détail du antigène APP Information d'application Stockage References for anti-APP antibody (ABIN3043787) Images
Fonction Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Séquence DAEFRHDSGY EVHHQKLVFF AEDVGSNKGA IIGLMVGGVV IA
Réactivité croisée (Details) No cross reactivity with other proteins.
Attributs du produit Rabbit IgG polyclonal antibody for Amyloid beta A4 protein(APP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: amyloid beta (A4) precursor protein
Protein Name: Amyloid beta A4 protein
Purification Immunogen affinity purified.
Immunogène A synthetic peptide corresponding to a sequence at the C-terminus of human APP(672-713aa DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA), different from the related mouse and rat sequences by three amino acids.
Isotype IgG

Détail du antigène APP

Détail du produit anti-APP anticorps Information d'application Stockage References for anti-APP antibody (ABIN3043787) Images Haut de la page
Antigène
Autre désignation APP (APP Antibody Extrait)
Sujet Beta Amyloid, also called Abeta or Abeta, denotes peptides of 36-43 amino acidsthat are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. It is mapped to 19q13.12. Several potential activities have been discovered for beta Amyloid, including activation of kinase enzymes, functioning as atranscription factor, and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatoryactivity). Moreover, monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity.

Synonyms: A4 antibody|A4 antibody|A4_HUMAN antibody|AAA antibody|AAA antibody|ABETA antibody|ABETA antibody|ABPP antibody|ABPP antibody|AD1 antibody|AICD-50 antibody|AICD-57 antibody|AICD-59 antibody|AID(50) antibody|AID(57) antibody|AID(59) antibody|Alzheimer disease amyloid protein antibody|Alzheimers Disease Amyloid Protein antibody|Amyloid B antibody|amyloid beta (A4) precursor protein antibody|amyloid beta A4 protein antibody|Amyloid Beta A4 Protein Precursor antibody|Amyloid Beta antibody|Amyloid intracellular domain 50 antibody|Amyloid intracellular domain 57 antibody|Amyloid intracellular domain 59 antibody|Amyloid of Aging and Alzheimer Disease antibody|APP antibody|APPI antibody|APPI antibody|B Amyloid antibody|Beta APP antibody|beta-amyloid peptide antibody|Beta-APP40 antibody|Beta-APP42 antibody|C31 antibody|Cerebral Vascular Amyloid Peptide antibody|CTFgamma antibody|CVAP antibody|CVAP antibody|Gamma-CTF(50)antibody|Gamma-CTF(57) antibody|Gamma-CTF(59) antibody|peptidase nexin-II antibody|PN II antibody|PN-II antibody|PN2 antibody|PreA4 antibody|PreA4 antibody|Protease nexin II antibody|Protease nexin-II antibody|S-APP-alpha antibody|S-APP-beta antibody
ID gène 351
UniProt P05067
Pathways Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

Information d'application

Détail du produit anti-APP anticorps Détail du antigène APP Stockage References for anti-APP antibody (ABIN3043787) Images Haut de la page
Indications d'application WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for APP is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Commentaires

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Stockage

Détail du produit anti-APP anticorps Détail du antigène APP Information d'application References for anti-APP antibody (ABIN3043787) Images Haut de la page
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-APP antibody (ABIN3043787)

Détail du produit anti-APP anticorps Détail du antigène APP Information d'application Stockage Images Haut de la page
Produit citée dans:

Sun, Zhou, Yi, Jiang, Yuan: "Lead-induced morphological changes and amyloid precursor protein accumulation in adult rat hippocampus." dans: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 513-7, 2014

Qin, Yao, Huang: "Effects of compound danshen tablets on spatial cognition and expression of brain beta-amyloid precursor protein in a rat model of Alzheimer's disease." dans: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine, Vol. 32, Issue 1, pp. 63-6, 2012

Li, Li, Huang, Kan, Wang, Wu, Yin, Yao: "Dexamethasone and A???-?? accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats." dans: Behavioural brain research, Vol. 227, Issue 1, pp. 142-9, 2011

Nie, Luo, Huang, Gong, Wu, Shi: "Icariin inhibits beta-amyloid peptide segment 25-35 induced expression of beta-secretase in rat hippocampus." dans: European journal of pharmacology, Vol. 626, Issue 2-3, pp. 213-8, 2009

Images

Détail du produit anti-APP anticorps Détail du antigène APP Information d'application Stockage References for anti-APP antibody (ABIN3043787) Haut de la page
Supplier Images
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, IHC(P): Mouse Brain Tissue
Immunohistochemistry (IHC) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, IHC(P): Rat Brain Tissue
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, All lanes: Anti beta Amyloid at 0.5ug/ml WB: R...
Western Blotting (WB) image for anti-Amyloid beta (A4) Precursor Protein (APP) (AA 672-713), (C-Term) antibody (ABIN3043787) Anti-beta Amyloid Picoband antibody, All lanes: Anti beta Amyloid at 0.5ug/ml Lane ...