HLA-DR-gamma Produits
(HLA-DR-gamma (CD74))
Catégories
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Catégories HLA-DR-gamma en vedette
HLA-DR-gamma Anticorps
High quality antibodies with extensive validation data.
HLA-DR-gamma Kits ELISA
Reliable ELISA kits for a wide range of species.
HLA-DR-gamma Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HLA-DR-gamma recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS, ELISA, ICC
Validations
- (2)
- (6)
N° du produit
ABIN1724871
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
IF, IHC
Validations
- (9)
N° du produit
ABIN7074245
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7443692
Quantité
100 μL
Fiche technique
Fiche technique
HLA-DR-gamma recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962624
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967449
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956587
Quantité
96 tests
Fiche technique
Fiche technique
HLA-DR-gamma recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274222
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274239
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1348699
Quantité
25 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HLA-DR-gamma
: "Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy." dans: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).: "Examining epitope mutagenesis as a strategy to reduce and eliminate human antibody binding to class II swine leukocyte antigens." dans: Immunogenetics, Vol. 71, Issue 7, pp. 479-487, (2019) (PubMed).
: "Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning." dans: Scientific reports, Vol. 9, Issue 1, pp. 13877, (2019) (PubMed).
: "Examining the Biosynthesis and Xenoantigenicity of Class II Swine Leukocyte Antigen Proteins." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 8, pp. 2957-2964, (2018) (PubMed).
: "Expression of macrophage migration inhibitory factor and CD74 in the inner ear and middle ear in lipopolysaccharide-induced otitis media." dans: Acta oto-laryngologica, Vol. 136, Issue 10, pp. 1011-6, (2016) (PubMed).
: "Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-γ." dans: The Journal of investigative dermatology, Vol. 135, Issue 11, pp. 2775-84, (2015) (PubMed).
: "A conserved WW domain-like motif regulates invariant chain-dependent cell-surface transport of the NKG2D ligand ULBP2." dans: Molecular immunology, Vol. 66, Issue 2, pp. 418-27, (2015) (PubMed).
: "Autoantibodies against CD74 in spondyloarthritis." dans: Annals of the rheumatic diseases, Vol. 73, Issue 6, pp. 1211-4, (2014) (PubMed).
: "Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells." dans: Biochemical and biophysical research communications, Vol. 451, Issue 1, pp. 48-53, (2014) (PubMed).
: "CD74: a new prognostic factor for patients with malignant pleural mesothelioma." dans: British journal of cancer, Vol. 110, Issue 8, pp. 2040-6, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à HLA-DR-gamma
CD74 molecule (CD74), CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), CD74 molecule (Cd74), CD74 molecule, major histocompatibility complex, class II invariant chain a (cd74a), CD74 molecule, major histocompatibility complex, class II invariant chain b (cd74b), cd74, CLIP, DHLAG, HLADG, Ia-GAMMA, Iclp-1, Iclp-2, iclp1, iclp2, II, Ii, INVG34, wu:fb11f09, wu:fb12a01, wu:fb13d06, wu:fk94e07, zgc:123161Protein level used designations for HLA-DR-gamma
- CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
- HLA class II histocompatibility antigen gamma chain
- HLA-DR antigens-associated invariant chain
- HLA-DR-gamma
- Ia-associated invariant chain
- MHC HLA-DR gamma chain
- gamma chain of class II antigens
- p33
- H-2 class II histocompatibility antigen gamma chain
- HLA-DR-GAMMA
- MHC class II-associated invariant chain
- class II-associated invariant chain peptide
- dinucleotide microsatellite
- histocompatibility: class II antigens, gamma chain of
- ia antigen-associated invariant chain
- invariant polypeptide of major histocompatibility complex, class II antigen-associated
- ii
- CD74 molecule, major histocompatibility complex, class II invariant chain
- CD74 molecule, major histocompatibility complex, class II invariant chain a
- MHC II
- invariant chain-like protein 1
- invariant chain-like protein 2
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