RANKL Kit ELISA

N° du produit ABIN2042623

Détail du produit RANKL Kit ELISA

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 93.7-6000 pg/mL

Seuil minimal de détection: 93.7 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 5 pg/mL

Ingrédients: 96-well plate pre-coated with anti-OPG, Mouse
Lyophilized recombinant OPG, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Mouse OPG in cell culture supernates, serum and plasma (EDTA).Osteoprotegerin (OPG) is identical to osteoclastogenesis inhibitory factor (OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis.1 OPG is considered to play an important role in the regulation of bone resorption by modifying osteoclast differentiation.2 Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease.3 It can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.4 OPG system may play a critical role in the development of osteolytic bone disease in multiple myeloma and that targeting this system may have therapeutic potential.5 OPG also plays a role in the vascular system.6

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Autre désignation: OPG (TNFSF11 Produits)

Synonymes: CD254 Kit ELISA, ODF Kit ELISA, OPGL Kit ELISA, OPTB2 Kit ELISA, RANKL Kit ELISA, TRANCE Kit ELISA, hRANKL2 Kit ELISA, sOdf Kit ELISA, TNFSF11 Kit ELISA, Ly109l Kit ELISA, OPG Kit ELISA, Trance Kit ELISA, cd254 Kit ELISA, odf Kit ELISA, opgl Kit ELISA, optb2 Kit ELISA, rankl Kit ELISA, sodf Kit ELISA, tnfsf11 Kit ELISA, trance Kit ELISA, TNF superfamily member 11 Kit ELISA, tumor necrosis factor (ligand) superfamily, member 11 Kit ELISA, TNF receptor superfamily member 11b Kit ELISA, TNF superfamily member 11 L homeolog Kit ELISA, TNFSF11 Kit ELISA, Tnfsf11 Kit ELISA, TNFRSF11B Kit ELISA, tnfsf11.L Kit ELISA

ID gène: 18383

UniProt: O08712

Pathways: Signalisation NF-kappaB