RANKL Kit ELISA

N° du produit ABIN2042701

Détail du produit RANKL Kit ELISA

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 62.5-4000 pg/mL

Seuil minimal de détection: 62.5 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 10 pg/mL

Ingrédients: 96-well plate pre-coated with anti-TNFSF11/RANKL, Mouse
Lyophilized recombinant TNFSF11/RANKL, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Mouse TNFSF11/RANKL in cell culture supernates, serum and plasma (heparin, EDTA).Receptor activator of nuclear factor kappa-B ligand(RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), is a protein that in humans is encoded by the TNFSF11 gene. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This gene is mapped to chromosome13q14.11. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. This gene may play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Autre désignation: TNFSF11ANKL (TNFSF11 Produits)

Synonymes: CD254 Kit ELISA, ODF Kit ELISA, OPGL Kit ELISA, OPTB2 Kit ELISA, RANKL Kit ELISA, TRANCE Kit ELISA, hRANKL2 Kit ELISA, sOdf Kit ELISA, TNFSF11 Kit ELISA, Ly109l Kit ELISA, OPG Kit ELISA, Trance Kit ELISA, cd254 Kit ELISA, odf Kit ELISA, opgl Kit ELISA, optb2 Kit ELISA, rankl Kit ELISA, sodf Kit ELISA, tnfsf11 Kit ELISA, trance Kit ELISA, TNF superfamily member 11 Kit ELISA, tumor necrosis factor (ligand) superfamily, member 11 Kit ELISA, TNF receptor superfamily member 11b Kit ELISA, TNF superfamily member 11 L homeolog Kit ELISA, TNFSF11 Kit ELISA, Tnfsf11 Kit ELISA, TNFRSF11B Kit ELISA, tnfsf11.L Kit ELISA

ID gène: 21943

UniProt: O35235

Pathways: Signalisation NF-kappaB