Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.

Aperçu des produits pour anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) Anticorps

Full name:: anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 Anticorps (TNFRSF4)

Chez www.anticorps-enligne.fr sont 231 Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) Anticorps de 27 de différents fournisseurs disponibles. De plus, nous expédions Tumor Necrosis Factor Receptor Superfamily, Member 4 Protéines (68) et Tumor Necrosis Factor Receptor Superfamily, Member 4 Kits (14) et beaucoup plus de produits pour cette protéine. Un total de 324 Tumor Necrosis Factor Receptor Superfamily, Member 4 produits sont actuellement listés.

Synonymes:: ACT35, CD134, Ly-70, OX40, TNFRSF4, Txgp1, TXGP1L

afficher tous les anticorps	Gène	GeneID	UniProt
	TNFRSF4	22163	P47741
	TNFRSF4	7293	P43489
	TNFRSF4	25572	P15725
Afficher toutes les espèces Afficher tous les synonymes

Réactivités les plus populaires pour anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) Anticorps

Sélectionnez vos espèces et l'application

anti-Mouse (Murine) Anticorps:

anti-Human Anticorps:

anti-Rat (Rattus) Anticorps:

Tous anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 Anticorps disponible

Vous arrivez à notre recherche pré-filtrée.

Pathways pertinentes pour anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 Anticorps

Plus produit pour Tumor Necrosis Factor Receptor Superfamily, Member 4 Anticorps

anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 Anticorps mieux référencés

Mouse (Murine) Monoclonal TNFRSF4 Primary Antibody pour IHC (fro), FACS - ABIN1177295 : Akiba, Oshima, Takeda, Atsuta, Nakano, Nakajima, Nohara, Yagita, Okumura: CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. dans Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
Show all 8 Pubmed References
Mouse (Murine) Monoclonal TNFRSF4 Primary Antibody pour FACS - ABIN2688959 : Baum, Gayle, Ramsdell, Srinivasan, Sorensen, Watson, Seldin, Baker, Sutherland, Clifford: Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34. dans The EMBO journal 1994 (PubMed)
Show all 8 Pubmed References
Human Monoclonal TNFRSF4 Primary Antibody pour IHC (f), FACS - ABIN2749179 : Jones, Fletcher, Pulford, Shahsafaei, Dorfman: The T-cell activation markers CD30 and OX40/CD134 are expressed in nonoverlapping subsets of peripheral T-cell lymphoma. dans Blood 1999 (PubMed)
Show all 7 Pubmed References
Human Monoclonal TNFRSF4 Primary Antibody pour IHC (f), FACS - ABIN2749174 : Aten, Roos, Claessen, Schilder-Tol, Ten Berge, Weening: Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis. dans Journal of the American Society of Nephrology : JASN 2000 (PubMed)
Show all 7 Pubmed References
Rat (Rattus) Monoclonal TNFRSF4 Primary Antibody pour FACS - ABIN2688958 : Weinberg, Vella, Croft: OX-40: life beyond the effector T cell stage. dans Seminars in immunology 1999 (PubMed)
Show all 4 Pubmed References
Human Monoclonal TNFRSF4 Primary Antibody pour FACS, ELISA - ABIN610382 : Kirchhausen, Nathanson, Matsui, Vaisberg, Chow, Burne, Keen, Davis: Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2. dans Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
Show all 3 Pubmed References
Cat (Feline) Monoclonal TNFRSF4 Primary Antibody pour FACS, WB - ABIN2478387 : Plutner, Cox, Pind, Khosravi-Far, Bourne, Schwaninger, Der, Balch: Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. dans The Journal of cell biology 1991 (PubMed)
Show all 4 Pubmed References
Cat (Feline) Monoclonal TNFRSF4 Primary Antibody pour FACS - ABIN2478389 : Stüber, Strober: The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response. dans The Journal of experimental medicine 1996 (PubMed)
Show all 4 Pubmed References
Cat (Feline) Monoclonal TNFRSF4 Primary Antibody pour FACS - ABIN2478390 : de Parseval, Chatterji, Sun, Elder: Feline immunodeficiency virus targets activated CD4+ T cells by using CD134 as a binding receptor. dans Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
Show all 4 Pubmed References
Cat (Feline) Monoclonal TNFRSF4 Primary Antibody pour FACS - ABIN2478392 : Willett, McMonagle, Logan, Spiller, Schneider, Hosie: Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand. dans Journal of virology 2007 (PubMed)
Show all 4 Pubmed References

Plus d’anticorps contre Tumor Necrosis Factor Receptor Superfamily, Member 4 partenaires d’interaction

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) interaction partners

OX40 is a key regulator of both intrahepatic innate and adaptive immunity.
OX40 can also activate the AKT-mTOR pathway, especially in the absence of BATF3 and BATF, to inhibit Foxp3 induction.
IL-2 promoted OX40 expression by downregulating the PPARalpha binding to the OX40 promoter.
The OX40 plays both redundant and distinct roles in regulating Regulatory T cells (Treg) plasticity in tissues.
Anti-PD-1 and anti PDL-1 do not increase the formation of ADA, but anti-CTLA-4 and anti-OX-40 do increase the onset of ADA.
The authors established that OX40L/OX40 interaction was required and sufficient to induce regulatory T-cell proliferation in vivo independent of PKC- status. Although PKC- is dispensable for T-cell receptor-independent regulatory T-cell proliferation per se, it is essential for optimum IL-2 production by effector T-cells.
Crucial role of OX40/OX40L signaling in a murine model of asthma has been demonstrated.
Combination therapies that depend on checkpoint inhibitor antibodies (Abs) such as for PD-1 or its ligand (PD-L1) together with immune stimulatory agonist Abs like anti-OX40 are being tested in the clinic to achieve improved antitumor effects
High Fat Diet-induced obese mice exhibit increased OX40 expression in adipose tissues and splenic T cells.
These data support the hypothesis that the Ox40/Ox40L pathway drives cellular and humoral autoimmune responses during lupus nephritis in NZB/W F1 mice and emphasize the potential clinical value of targeting this pathway in human lupus.
OX40 is a death receptor for invariant natural killer T cells and is implicated in pyroptotic cell death.
this study shows that OX40 links a costimulatory receptor to a repressive chromatin remodeling pathway, and that that OX40 stimulation inhibits IL-17 and reduces experimental autoimmune encephalomyelitis
IFNalphaR1 signaling promoted CXCL9 and CXCL10 synthesis, suggesting that these chemokines might be involved in the LPS and CD134 costimulation response.
OX40 and ICOS act in a cooperative, nonredundant manner to maximize and prolong the T follicular helper cell response that is generated after acute virus infection
OX40 regulates cardiac remodelling via the modulation of CD4(+) T-lymphocytes.
bone marrow-derived mast cell (BMMC)-exosomes facilitated the differentiation of naive CD4+ T cells to Th2 cells by ligation of OX40L and OX40 between BMMC-exosomes and CD4+ T cells and represents a novel mechanism of cell-to-cell communication
Crystal structures and NMR data show that the Roquin-1 ROQ domain recognizes hexaloops in the SELEX-derived alternative decay element (ADE) and in an ADE-like variant present in the Ox40 3'-UTR with identical binding modes.
The OX40-OX40 ligand interaction up-regulates intracellular levels of reactive oxygen species in atherogenesis.
OX40 was highly expressed by intratumoral T cells, particularly those of the FoxP3(+) regulatory T-cell (Treg) lineage.
OX40 and IL-7 play synergistic, but distinct roles in the homeostatic proliferation of CD4(+) effector memory T cells

Human Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) interaction partners

OX40 is a key regulator of both intrahepatic innate and adaptive immunity.
Blockade of OX40L in DC-derived exosomes could inhibit exosome-mediated CD4+ T proliferation and Th2 differentiation.
increased expression levels of OX40 and OX40L were involved in the pathogenesis of Immune thrombocytopenia
Authors report that OX40 is expressed on leukemic blasts in a substantial percentage of patients with acute myeloid leukemia (AML) and that OX40 can, after stimulation with agonistic OX40 antibodies, mediate proliferation and release of cytokines that act as growth and survival factors for the leukemic cells.
High OX40 expression in Ovarian carcinoma is correlated with chemosensitivity and improved recurrence free survival in Ovarian carcinoma . Patients might therefore benefit from a second line therapy.
Increased OX40 expression is associated with gastric cancer.
this study demonstrates that cSCCs contain an abundance of Tregs which can suppress tumoral effector T cell function and that activation of the costimulatory receptor OX40 enhances tumoral T cell responses.
OX40 expression on T cells was positively associated with obesity in humans.
Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection.
OX40 and OX40L formed a functional complex, which may facilitate signal transduction from OX40L to OX40 and contribute to the pathogenesis of Grave's disease.
this study investigated whether CD134 is preferentially expressed on CD4 T cells in drug-induced hypersensitivity syndrome .
blocking of both OX-40L and 4-1BBL reversed radiation-enhanced T-cell killing of human tumor targets as well as T-cell survival and activation.
Low OX40 expression is associated with colorectal cancer.
OX40 and its ligand are co stimulators for T lymphocytes.
These studies provide the first direct evidence that ligation of tumour necrosis factor superfamily members and their cognate receptors is important for the control of viral lytic replication.
Malaria patients and Plasmodium-infected rodents exhibit enhanced expression of the co-stimulatory receptor OX40 on CD4 T cells, which is abrogated following coordinate PD-1 co-inhibitory pathways, which are also upregulated during malaria.
Identified two key amino acid residues within CD134 that are required for its interaction with herpesvirus 6B (HHV-6B) and for HHV-6B entry into cells. One of the residues (K79) allows access of the HHV-6B ligand to CD134.
TL1A increases expression of CD25, LFA-1, CD134 and CD154, and induces IL-22 and GM-CSF production from effector CD4 T-cells
contributes to the aberrant T Follicular Helper response in systemic lupus erythematosus
Data indicate that soluble OX40 and sOX40L plasma levels are increased in early rheumatoid arthritis patients.

Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) profil antigène

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

Alternative names and synonyms associated with Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4)

TNF receptor superfamily member 4 (TNFRSF4) anticorps
tumor necrosis factor receptor superfamily, member 4 (Tnfrsf4) anticorps
TNF receptor superfamily member 4 (Tnfrsf4) anticorps

ACT35 anticorps
CD134 anticorps
Ly-70 anticorps
OX40 anticorps
TNFRSF4 anticorps
Txgp1 anticorps
TXGP1L anticorps

Protein level used designations for TNFRSF4

tumor necrosis factor receptor superfamily, member 4 , tumor necrosis factor receptor superfamily member 4 , OX40 antigen , OX40L receptor , tax-transcriptionally activated glycoprotein 1 , ACT35 antigen , ATC35 antigen , CD134 antigen , OX40 cell surface antigen , OX40 homologue , TAX transcriptionally-activated glycoprotein 1 receptor , lymphoid activation antigene ACT35 , tax-transcriptionally activated glycoprotein 1 receptor , MRC OX40 , Tax-transcriptionally activated glycoprotein 1 , tumor necrosis factor (ligand) superfamily member 4 , tumor necrosis factor superfamily, member 4

GENE ID	SPECIES
457185	Pan troglodytes
489600	Canis lupus familiaris
528782	Bos taurus
699674	Macaca mulatta
22163	Mus musculus
493665	Felis catus
7293	Homo sapiens
25572	Rattus norvegicus

Fournisseurs de qualité sélectionnés pour anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) Anticorps

Avez-vous cherché autre chose?

Tel:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@anticorps-enligne.fr

Show all anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) Anticorps with Pubmed References

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) interaction partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) interaction partners

Antigen Summary

Alternative names and synonyms associated with Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4)

Protein level used designations for TNFRSF4