TNFSF9 Protein (AA 52-254, partial) (His tag)

N° du produit ABIN1046589

Détail du produit

Antigène: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Type de proteíne: Recombinant

Attributs du protein: AA 52-254, partial

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TNFSF9 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS), ELISA

Séquence: PWAVSGARAS PGSAASPRLR EGPELSPDDP AGLLDLRQGM FAQLVAQNVL LIDGPLSWYS DPGLAGVSLT GGLSYKEDTK ELVVAKAGVY YVFFQLELRR VVAGEGSGSV SLALHLQPLR SAAGAAALAL TVDLPPASSE ARNSAFGFQG RLLHLSAGQR LGVHLHTEAR ARHAWQLTQG ATVLGLFRVT PEIPAGLPSP RSE

Attributs du produit: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Pureté: 90 %

Information d'application

Commentaires:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0, 200 mM Imidazole

Stock: -20 °C

Référence

Won, Cha, Byun, Kim, Shin, Ahn, Kim, Rice, Walz, Kwon, Cho: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." dans: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Alderson, Smith, Tough, Davis-Smith, Armitage, Falk, Roux, Baker, Sutherland, Din: "Molecular and biological characterization of human 4-1BB and its ligand." dans: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, (1994) (PubMed).

Détail du antigène

Antigène: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Abstract: TNFSF9 Produits

Synonymes: TNFSF9 Protein, 4-1BB-L Protein, 4-1BBL Protein, AI848817 Protein, Cd137l Protein, Ly63l Protein, CD137L Protein, TNF superfamily member 9 Protein, tumor necrosis factor (ligand) superfamily, member 9 Protein, Tnfsf9 Protein, LOC476729 Protein, TNFSF9 Protein

Sujet: Synonyms: 4-1BB ligand,4-1BBL

Poids moléculaire: 25.4 kD

UniProt: Q07011

Pathways: Activated T Cell Proliferation, Cancer Immune Checkpoints