PSMC3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2729967

Détail du produit

Antigène: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PSMC3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PSMC3 / TBP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Autre désignation: Psmc3,tbp1 (PSMC3 Produits)

Synonymes: TBP1 Protein, TBP-1 Protein, wu:fb39a02 Protein, zgc:86713 Protein, psmc3 Protein, MGC89608 Protein, PSMC3 Protein, NV15940 Protein, 23.m06430 Protein, DDBDRAFT_0186002 Protein, DDBDRAFT_0232967 Protein, DDB_0186002 Protein, DDB_0232967 Protein, psmc3-b Protein, tbp10 Protein, psmc3-a Protein, proteasome 26S subunit, ATPase 3 Protein, proteasome (prosome, macropain) 26S subunit, ATPase 3 Protein, 26S protease regulatory subunit 6A Protein, 26S protease regulatory subunit 6a Protein, 26S protease regulatory subunit 6A-B Protein, 26S protease regulatory subunit 6A, putative Protein, proteasome 26S subunit, ATPase 3 S homeolog Protein, nth-like DNA glycosylase 1 S homeolog Protein, PSMC3 Protein, Psmc3 Protein, HCAG_00069 Protein, GL50803_4365 Protein, EDI_316920 Protein, CpipJ_CPIJ006888 Protein, CpipJ_CPIJ006889 Protein, CpipJ_CPIJ010864 Protein, prs6a Protein, psmc3 Protein, LOC100115023 Protein, BBOV_IV004580 Protein, CGB_M2140W Protein, psmC3 Protein, LOC100637883 Protein, psmc3.S Protein, nthl1.S Protein

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Poids moléculaire: 49 kDa

NCBI Accession: NP_002795

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway