PDGFRA Protein (AA 24-524) (His tag)
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- Antigène Voir toutes PDGFRA Protéines
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 24-524
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PDGFRA protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- PDGFRa, 24-524aa, Human, His tag, E.coli
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PDGFRA Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
- Stock
- 4 °C
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- Antigène
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- Autre désignation
- PDGFRa (PDGFRA Produits)
- Synonymes
- AI115593 Protein, CD140a Protein, Pdgfr-2 Protein, APDGFR Protein, PDGFACE Protein, CD140A Protein, PDGFR-2 Protein, PDGFR2 Protein, RHEPDGFRA Protein, PDGFR Protein, PDGFR-A Protein, platelet derived growth factor receptor alpha Protein, platelet derived growth factor receptor, alpha polypeptide Protein, platelet-derived growth factor receptor, alpha polypeptide L homeolog Protein, platelet-derived growth factor receptor, alpha polypeptide Protein, PDGFRA Protein, Pdgfra Protein, pdgfra.L Protein
- Sujet
- PDGFRa, also known as platelet derived growth factor receptor alpha, is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This protein can bind to both A and B subunits of PDGF. It is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. Recombinant human PDGFRa protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Platelet-derived growth factor receptor alpha precursor, CD140A, PDGFR2, MGC74795, Rhe-PDGFRA. NCBI no.: NP_006197
- Poids moléculaire
- 58.4 kDa (522aa)
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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