MEK1 Protein (AA 1-393) (His tag)

N° du produit ABIN6388205

Détail du produit

Antigène: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-393

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette MEK1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPMPKKKPT PIQLNPAPDG SAVNGTSSAE TNLEALQKKL EELELDEQQR KRLEAFLTQK QKVGELKDDD FEKISELGAG NGGVVFKVSH KPSGLVMARK LIHLEIKPAI RNQIIRELQV LHECNSPYIV GFYGAFYSDG EISICMEHMD GGSLDQVLKK AGRIPEQILG KVSIAVIKGL TYLREKHKIM HRDVKPSNIL VNSRGEIKLC DFGVSGQLID SMANSFVGTR SYMSPERLQG THYSVQSDIW SMGLSLVEMA VGRYPIPPPD AKELELMFGC QVEGDAAETP PRPRTPGRPL SSYGMDSRPP MAIFELLDYI VNEPPPKLPS GVFSLEFQDF VNKCLIKNPA ERADLKQLMV HAFIKRSDAE EVDFAGWLCS TIGLNQPSTP THAAGVHHHH HH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Autre désignation: MAP2K1 (MAP2K1 Produits)

Synonymes: Mek1 Protein, CFC3 Protein, MAPKK1 Protein, MEK1 Protein, MKK1 Protein, PRKMK1 Protein, MEKK1 Protein, Prkmk1 Protein, mek-2 Protein, si:ch211-242m18.2 Protein, wu:fj56a12 Protein, wu:fj61b01 Protein, zgc:56557 Protein, ATMEK1 Protein, F20B18.180 Protein, F20B18_180 Protein, MAP kinase/ ERK kinase 1 Protein, MITOGEN ACTIVATED PROTEIN KINASE KINASE Protein, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Protein, NMAPKK Protein, MEK Protein, mitogen activated protein kinase kinase 1 Protein, mitogen-activated protein kinase kinase 1 Protein, mitogen-activated protein kinase kinase 1 L homeolog Protein, MAP kinase/ ERK kinase 1 Protein, Map2k1 Protein, MAP2K1 Protein, map2k1.L Protein, map2k1 Protein, MEK1 Protein

Sujet: MAP2K1, is a member of the bispecific protein kinase family, which acts as a mitogen-activated protein (MAP) kinase. It is expressed extensively and brain levels are very low. It is located upstream of the MAP kinase and stimulates the enzymatic activity of MAP kinases on a variety of extra-and-cellular signals. This protein, an essential component of the MAP kinase signaling pathway, is involved in many cellular processes such as proliferation, differentiation, transcriptional regulation and development. Recombinant human MAP2K1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 44.5kDa (402aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002746

UniProt: Q02750

Pathways: Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling