CCL2 Protein (AA 24-99) (His tag)

N° du produit ABIN666739

Détail du produit

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Type de proteíne: Recombinant

Attributs du protein: AA 24-99

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CCL2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CCL2/MCP-1, 24-99 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 20% glycerol

Stock: 4 °C

Détail du antigène

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Autre désignation: CCL2/MCP-1 (CCL2 Produits)

Synonymes: GDCF-2 Protein, HC11 Protein, HSMCR30 Protein, MCAF Protein, MCP-1 Protein, MCP1 Protein, SCYA2 Protein, SMC-CF Protein, AI323594 Protein, JE Protein, Scya2 Protein, Sigje Protein, MCP-1A Protein, MCP1A Protein, C-C motif chemokine ligand 2 Protein, chemokine (C-C motif) ligand 2 Protein, C-C motif chemokine 2 Protein, CCL2 Protein, Ccl2 Protein, LOC101120093 Protein

Sujet: Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant human CCL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MCAF, GDCF-2, HC11, SCYA2, Chemokine (C-C motif) ligand 2, CCL2, small inducible cytokine A2 (monocyte chemotactic protein 1 homologous to mouse Sig-je), MCP1, MCP-1, SMC-CF, MGC9434,. NCBI no.: NP_002973

Poids moléculaire: 10.9 kDa (97 aa), confirmed by MALDI-TOF.

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2