RAP1A Protein (AA 1-181) (His tag)

N° du produit ABIN667792

Détail du produit

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Type de proteíne: Recombinant

Attributs du protein: AA 1-181

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RAP1A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: RAP1A, 1-181aa, Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: RAP1A (RAP1A Produits)

Synonymes: KREV-1 Protein, KREV1 Protein, RAP1 Protein, SMGP21 Protein, AI848598 Protein, G-22K Protein, Krev-1 Protein, Rap1 Protein, RAP-1A Protein, rap 1A Protein, wu:fc66g06 Protein, zgc:86676 Protein, krev-1 Protein, krev1 Protein, rap1 Protein, RAP1A, member of RAS oncogene family Protein, RAS-related protein 1a Protein, RAP1A, member of RAS oncogene family a Protein, RAP1A, member of RAS oncogene family L homeolog Protein, RAP1A Protein, Rap1a Protein, rap1aa Protein, rap1a.L Protein

Sujet: Ras-related protein Rap-1A (RAP1A) belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. This Protein Induces morphological reversion of a cell line transformed by a Ras oncogene and Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Recombinant human RAP1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: KREV1, G-22K, C21KG, Ras-related protein Rap-1A, G 22K, GTP binding protein smg p21A, KREV 1, OTTHUMP00000013741, RAP 1A, RAP1, RAP1A member of RAS oncogene family , Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, SMGP21. NCBI no.: NP_001010935

Poids moléculaire: 22.8kDa (201aa) confirmed by MALDI-TOF

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor