BLK Protein (AA 1-505) (His tag)

N° du produit ABIN667955

Détail du produit

Antigène: BLK (B Lymphoid Tyrosine Kinase (BLK))

Type de proteíne: Recombinant

Attributs du protein: AA 1-505

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BLK protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: BLK, 1-505aa, Human, His tag, Hi-5

Pureté: > 80 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT,0.1mM PMSF

Stock: 4 °C

Détail du antigène

Antigène: BLK (B Lymphoid Tyrosine Kinase (BLK))

Autre désignation: BLK (BLK Produits)

Synonymes: bltk Protein, si:dkey-33i22.2 Protein, zgc:136231 Protein, MODY11 Protein, BLK proto-oncogene, Src family tyrosine kinase Protein, B lymphoid kinase Protein, blk Protein, BLK Protein, Blk Protein

Sujet: BLK, also known as B lymphoid kinase, is a 55kDa tyrosine kinase with SH3, SH2, and catalytic domains that contain consensus sequences of the Src protein tyrosine kinase family. This protein is expressed specifically in the B cell lineage and plays a role in the signaltransduction pathway that is restricted to B lymphoid cells. Recombinant human BLK protein was expressed with N-terminal His-tag in High-Five cells using baculovirus expression system and purified by using conventional chromatography techniques. Synonyms: Tyrosine-protein kinase Blk, MGC10442, MODY11. NCBI no.: NP_001706

Poids moléculaire: 59.8 kDa (525aa)

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling