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CD25 Protein (AA 22-236) (His tag)

IL2RA Origine: Souris Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
N° du produit ABIN6809868
  • Antigène Voir toutes CD25 (IL2RA) Protéines
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 22-236
    Origine
    • 17
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 13
    • 9
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD25 protéine est marqué à la His tag.
    Séquence
    AA 22-236
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL2RA Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
  • Antigène
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Autre désignation
    IL-2 R alpha (IL2RA Produits)
    Synonymes
    CD25 Protein, IDDM10 Protein, IL2R Protein, TCGFR Protein, IL2RAC Protein, IL-2RA Protein, Il2r Protein, Ly-43 Protein, interleukin 2 receptor subunit alpha Protein, interleukin-2 receptor subunit alpha-like Protein, interleukin 2 receptor, alpha chain Protein, IL2RA Protein, Il2ra Protein, LOC100222957 Protein
    Sujet
    Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.
    Poids moléculaire
    26.6 kDa
    NCBI Accession
    NP_032393
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation
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