PDK4 Protein (GST tag,His tag)
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- Antigène Voir toutes PDK4 Protéines
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
- Type de proteíne
- Recombinant
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Origine
- Souris
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette PDK4 protéine est marqué à la GST tag,His tag.
- Fonction
- Recombinant Mouse PDK4 Protein (His & GST Tag)(Active)
- Séquence
- Met1-Val412
- Attributs du produit
- A DNA sequence encoding the mouse PDK4 (O70571) (Met1-Val412) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Pureté
- > 85 % as determined by SDS-PAGE
- niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Kinase activity untested
- Top Product
- Discover our top product PDK4 Protéine
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Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 1-411) (Active) protein (GST tag)
PDK4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant SDS, Func Active
Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 138-368) protein (His tag)PDK4 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 1-411) protein (GST tag)PDK4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 181-280) protein (GST tag)PDK4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) proteinPDK4 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) protein (Myc-DYKDDDDK Tag)PDK4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
- Autre désignation
- PDK4 (PDK4 Produits)
- Synonymes
- AV005916 Protein, pyruvate dehydrogenase kinase 4 Protein, pyruvate dehydrogenase kinase, isoenzyme 4 Protein, pdk4 Protein, PDK4 Protein, Pdk4 Protein
- Sujet
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Background: Pyruvate dehydrogenase kinase 4 (PDK4) is a mitochondrial protein that regulates the TCA cycle.PDK4, a vital mitochondrial protein, controls the switch between glycolysis and oxidative phosphorylation based upon nutrient availability.Pyruvate dehydrogenase kinase 4 (PDK4) mRNA has been reported as an up-regulated gene in the heart and skeletal muscle of carnitine-deficient juvenile visceral steatosis (JVS) mice under fed conditions. PDK4 plays an important role in the inhibition of glucose oxidation via the phosphorylation of pyruvate dehydrogenase complex (PDC).PDK4 gene expression is stimulated by thyroid hormone (T(3)), glucocorticoids, and long chain fatty acids.
Synonym: AV005916
- Poids moléculaire
- 74.4 kDa
- UniProt
- O70571
- Pathways
- Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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