EGFRviii Protein (AA 25-378) (FITC,His-Avi Tag)

N° du produit ABIN7274519

Détail du produit

Antigène: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Type de proteíne: Recombinant

Attributs du protein: AA 25-378

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EGFRviii protéine est marqué à la FITC,His-Avi Tag.

Fonction: FITC-Labeled Human EGFRVIII Protein

Séquence: Leu25-Ser378

Attributs du produit: Recombinant FITC-Labeled Human EGFRVIII Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu25-Ser378.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Autre désignation: EGFRVIII (EGFRv3 Produits)

Sujet: The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.

Poids moléculaire: 41.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_001333870