NOTCH2 Protein (His-Avi Tag,Biotin)
-
- Antigène Voir toutes NOTCH2 Protéines
- NOTCH2 (Notch 2 (NOTCH2))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette NOTCH2 protéine est marqué à la His-Avi Tag,Biotin.
- Séquence
- Leu26-Gln530
- Pureté
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
-
Notch 2 (NOTCH2) (AA 26-530) (Active) protein (Fc Tag)
NOTCH2 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Notch 2 (NOTCH2) (AA 27-136) protein (GST tag)NOTCH2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Notch 2 (NOTCH2) protein (His tag)NOTCH2 Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- NOTCH2 (Notch 2 (NOTCH2))
- Autre désignation
- Notch 2 (NOTCH2 Produits)
- Synonymes
- AGS2 Protein, HJCYS Protein, hN2 Protein, AI853703 Protein, N2 Protein, notch6 Protein, sb:cb884 Protein, neurogenic locus notch homolog protein 2 Protein, notch 2 Protein, notch 3 Protein, LOC581186 Protein, NOTCH2 Protein, notch3 Protein, Notch2 Protein, notch2 Protein
- Sujet
- AGS2, Notch-2, NOTCH2, N2ECD, HJCYS, N2,Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of either Notch-1 or Notch-2 is lethal, showing that not all functions overlap.Notch-2 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
- Poids moléculaire
- 57 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- UniProt
- Q04721
- Pathways
- Signalisation Notch, Stem Cell Maintenance
-
