LRP6 Protein (His tag)

N° du produit ABIN7491293

Détail du produit

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LRP6 protéine est marqué à la His tag.

Fonction: Recombinant Human LRP6 Protein with C-terminal 6xHis tag

Specificité: LRP6 (Ala20-Ala1370) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Autre désignation: LRP6 (LRP6 Produits)

Synonymes: lrp6-A Protein, Xlrp6 Protein, adcad2 Protein, lrp6 Protein, LRP6 Protein, ADCAD2 Protein, C030016K15Rik Protein, Cd Protein, Gw Protein, LDL receptor related protein 6 Protein, LDL receptor related protein 6 L homeolog Protein, LDL receptor related protein 6 S homeolog Protein, low density lipoprotein receptor-related protein 6 Protein, low-density lipoprotein receptor-related protein 6 Protein, LRP6 Protein, lrp6.L Protein, lrp6.S Protein, lrp6 Protein, Lrp6 Protein, LOC590395 Protein

Sujet: ADCAD2, STHAG7
Description: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands.
Description: The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]

Poids moléculaire: predicted molecular mass of 153.1 kDa after removal of the signal peptide. The apparent molecular mass of LRP6-His is 130-250 kDa due to glycosylation.

UniProt: O75581

Pathways: Signalisation WNT, Tube Formation