Oncostatin M Receptor Protein (OSMR) (AA 28-740) (Fc Tag)

N° du produit ABIN7504493

Détail du produit

Antigène: Oncostatin M Receptor (OSMR)

Type de proteíne: Recombinant

Attributs du protein: AA 28-740

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Oncostatin M Receptor protéine est marqué à la Fc Tag.

Fonction: Human OSMR Protein

Séquence: Glu28-Met740

Attributs du produit: Recombinant Human OSMR Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Glu28-Met740.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Oncostatin M Receptor (OSMR)

Autre désignation: OSMR (OSMR Produits)

Synonymes: OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein

Sujet: OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.

Poids moléculaire: 107.06 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result.

Pathways: Signalistation JAK/STAT, Growth Factor Binding