p53 Protein (AA 25-305, Tetramer) (PE,His-Avi Tag,p53)
Aperçu rapide pour p53 Protein (AA 25-305, Tetramer) (PE,His-Avi Tag,p53) (ABIN7504498)
Antigène
Voir toutes p53 (TP53) ProtéinesType de proteíne
Origine
Source
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Attributs du protein
- AA 25-305, Tetramer
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Purification/Conjugué
- Cette p53 protéine est marqué à la PE,His-Avi Tag,p53.
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Fonction
- PE-Labeled Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein
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Séquence
- Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and HMTEVVRRC peptide
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Specificité
- Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), HMTEVVRRC
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Attributs du produit
- Recombinant PE-Labeled Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin. It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and HMTEVVRRC peptide.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 12.751,56 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 15.754,29 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
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Tumor Protein P53 (TP53) (AA 1-393) protein (His tag)
custom-made TP53 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Protein P53 (TP53) (AA 1-393) protein (GST tag)TP53 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Protein P53 (TP53) (Active) protein (His tag)TP53 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant STD, PI, in vitro Active
Tumor Protein P53 (TP53) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TP53 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP
Tumor Protein P53 (TP53) (AA 1-391) protein (His tag)TP53 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Tumor Protein P53 (TP53) protein (His-SUMO Tag)TP53 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90% as determined by SDS-PAGE. ELISA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS, 0.2 % BSA ( pH 7.4).
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Stock
- -80 °C
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Stockage commentaire
- Valid for 6 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles and protect from light.
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Date de péremption
- 12 months
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Autre désignation
- P53
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Sujet
- P53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
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UniProt
- A0A140T913
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Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
Antigène
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