anti-Boeuf (Vache) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 anticorps pour Western Blotting

Recommended ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Anticorps
  • ABC21
  • GBD1
  • ICP3
  • MDR2
  • MDR2/3
  • MDR3
  • PFIC-3
  • PGY3
  • zgc:172149
  • Mdr2
  • Pgy-2
  • Pgy2
  • mdr-2
  • Pgy3
  • ABCB4a
  • Abcb4
  • Evi32
  • Mdr1a
  • Mdr3
  • P-gp
  • Pgp
  • Pgy-3
  • mdr-3
  • DEFB1
  • PGP3
  • ABCB4
  • RUNDC3B
  • ATP binding cassette subfamily B member 4
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A
  • beta-defensin 1-like
  • RUN domain-containing protein 3B
  • ABCB4
  • abcb4
  • Abcb4
  • Abcb1a
  • LOC100861170
  • LOC101122517
Épitope
N-Term
9
8
7
5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Porc, Lapin, Rat (Rattus), Mouton
36
23
7
2
2
2
1
1
1
1
1
Hôte
Lapin
39
8
2
2
Clonalité
Polyclonal
Conjugué
Inconjugué
4
4
3
1
1
1
Application
Western Blotting (WB)
41
21
16
9
6
4
4
3
3
1
Options
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N° du produit ABIN2776966
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
2.9820433 ABIN2776967 WB Rabbit Middle Region Connectez-vous pour afficher Polyclonal 1
1 ABIN768867 IHC IHC (p) WB Rabbit AA 252-301 Connectez-vous pour afficher Polyclonal 0

General

Antigène ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Anticorps
Épitope N-Term
(9), (8), (7), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Porc, Lapin, Rat (Rattus), Mouton
(36), (23), (7), (2), (2), (2), (1), (1), (1), (1), (1)
Hôte Lapin
(39), (8), (2), (2)
Clonalité
Polyclonal
Conjugué Inconjugué
(4), (4), (3), (1), (1), (1)
Application Western Blotting (WB)
(41), (21), (16), (9), (6), (4), (4), (3), (3), (1)
Pubmed 1 référence disponible
Fournisseur Connectez-vous pour afficher

Détail du produit

Détail du antigène Information d'application Stockage Référence Images
Blocking Peptide Blocking peptide for this product available: ABIN972723
Séquence AGAVAEEALG AIRTVIAFGG QNKELERYQK HLENAKEIGI KKAISANISM
Homologie Cow: 86%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 77%
Attributs du produit This is a rabbit polyclonal antibody against ABCB4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogène The immunogen is a synthetic peptide directed towards the N terminal region of human ABCB4

Détail du antigène

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Antigène
Autre désignation ABCB4 (ABCB4 Antibody Extrait)
Sujet ABCB4, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. ABCB4 is a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined, however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Alias Symbols: ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Protein Interaction Partner: PIGY, TESK1, HAX1,
Protein Size: 1279
Poids moléculaire 141 kDa
ID gène 5244
NCBI Accession NM_000443, NP_000434
UniProt A4D1D4
Pathways Regulation of Lipid Metabolism by PPARalpha

Information d'application

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Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 1279 AA

Restrictions For Research Use only

Stockage

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Référence

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Background publications

Floreani, Carderi, Paternoster, Soardo, Azzaroli, Esposito, Montagnani, Marchesoni, Variola, Rosa Rizzotto, Braghin, Mazzella: "Hepatobiliary phospholipid transporter ABCB4, MDR3 gene variants in a large cohort of Italian women with intrahepatic cholestasis of pregnancy." dans: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 40, Issue 5, pp. 366-70, 2008

Images

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Images (Fournisseur)
Western Blotting (WB) image for anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (N-Term) antibody (ABIN2776966) Host: Rabbit
Target Name: ABCB4
Sample Tissue: 293T Whole Cell
L...