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anti-Human HMGB1 Anticorps:
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Cow (Bovine) Polyclonal HMGB1 Primary Antibody pour ELISA, FACS - ABIN250703
Barlan, Griffin, McGuire, Wiethoff: Adenovirus membrane penetration activates the NLRP3 inflammasome. dans Journal of virology 2010
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Human Monoclonal HMGB1 Primary Antibody pour CyTOF, FACS - ABIN4899428
Liou, Adler, Keogh, Li, Jensen, Walsh, Packer, Clark, Carveth, Chen, Rogers, Lane, Moore, Sturrock, Paine, Cox, Hoidal: Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis. dans PLoS ONE 2012
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Human Polyclonal HMGB1 Primary Antibody pour IF (p), IHC (p) - ABIN671616
Zhao, Hu, Sun, Sun: The high mobility group box 1 protein of Sciaenops ocellatus is a secreted cytokine that stimulates macrophage activation. dans Developmental and comparative immunology 2011
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Human Monoclonal HMGB1 Primary Antibody pour IF, IHC (p) - ABIN561281
Krüger, Krick, Dhillon, Lerner, Ames, Bromberg, Lin, Walsh, Vella, Fischereder, Krämer, Colvin, Heeger, Murphy, Schröppel: Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. dans Proceedings of the National Academy of Sciences of the United States of America 2009
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Human Polyclonal HMGB1 Primary Antibody pour ELISA, ICC - ABIN6269456
Wang, Sun, Li, Deng, Zeng, Tao, Wang, Guan, Zhao: Urinary MCP-1、HMGB1 increased in calcium nephrolithiasis patients and the influence of hypercalciuria on the production of the two cytokines. dans Urolithiasis 2016
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Human Polyclonal HMGB1 Primary Antibody pour IHC (p), WB - ABIN5518759
Bi, Zhu, Yan, Chen, Wang, Ma, Yang: Association of Upregulated HMGB1 and c-IAP2 Proteins With Hepatocellular Carcinoma Development and Progression. dans Hepatitis monthly 2015
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Human Monoclonal HMGB1 Primary Antibody pour IF, IHC (p) - ABIN1326935
Kim, Ku, Bae: Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLP-induced sepsis mice. dans Journal of cellular physiology 2013
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Human Monoclonal HMGB1 Primary Antibody pour IF, IHC (p) - ABIN561286
Zhou, Huang, Poon, Chen, Chan, Ng, Guan, Watt, Lu, Yuen, Zheng: Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection. dans Journal of hepatology 2009
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Human Monoclonal HMGB1 Primary Antibody pour IF, IHC (p) - ABIN561282
Franciosi, Govorukhina, Fusetti, Poolman, Lodewijk, Timens, Postma, ten Hacken, Bischoff: Proteomic analysis of human epithelial lining fluid by microfluidics-based nanoLC-MS/MS: a feasibility study. dans Electrophoresis 2013
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Hamster Monoclonal HMGB1 Primary Antibody pour FACS, IF - ABIN2474000
Lange, Vasquez: HMGB1: the jack-of-all-trades protein is a master DNA repair mechanic. dans Molecular carcinogenesis 2009
This work indicates that NELL-1 (Montrer NELL1 Anticorps), HMGB1, and CCN2 (Montrer CTGF Anticorps) might enhance bone defect healing via the recruitment of endogenous cells and induction of vascularization and act via different processes than BMP2 (Montrer BMP2 Anticorps).
comparison of inhibitory potential of the already known inhibitors of Head and neck squamous cell carcinoma against HMGB1-binding pocket using simulations and docking.
identified 2 novel miR (Montrer MLXIP Anticorps)-193a-3p targets, the high mobility group box-1 (HMGB1) and the hypoxia upregulated-1 (HYOU1 (Montrer HYOU1 Anticorps)) gene products. HMGB1 silencing in cord blood ECFC-derived cells confirmed its role in regulating vascular function.
Results show that HMGB1 is highly expressed in prostate cancer (PC) tissues. Highly expressed HMGB1 activates RAGE (Montrer AGER Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) signaling pathways, which facilitates the metastasis of prostate cancer.
HMGB1 was identified as a down-stream target of miR (Montrer MLXIP Anticorps)-204. The miR (Montrer MLXIP Anticorps)-204/HMGB1 axis mediated ZEB2 (Montrer ZEB2 Anticorps)-AS1's (Montrer ARSB Anticorps) effect on pancreatic cancer.
Study demonstrated that HMGB1 and TLR4 (Montrer TLR4 Anticorps) could contribute to the inflammatory lichen planus process in skin.
Our research shows that HMGB1 participates in autophagy and DNA damage repair and that downregulation of HMGB1 enhances the sensitivity of multiple myeloma (MM)cells to Dex, suggesting that HMGB1 may serve as a target for MM treatment.
HMGB1 plays a critical role in mitochondrial autophagy in cardiomyocytes. miR (Montrer MLXIP Anticorps)-410 targets its 3'UTR (Montrer UTS2R Anticorps) and regulates its transcription.
HMGB1 is a good diagnostic biomarker for differentiating refractory M. pneumoniae pneumonia and non-refractory M. pneumoniae pneumonia.
HMGB1 promoted lung cancer invasion and metastasis by upregulating the expression and activity of MMP-2 (Montrer MMP2 Anticorps) in an NF-kappaB (Montrer NFKB1 Anticorps)-dependent manner.
a new pathway for the activation of Treg involving in tumor-derived HMGB1 and TSLP (Montrer TSLP Anticorps), and have important implications for incorporating HMGB1 inhibitors into cancer immunotherapy.
HMGB1 plays a novel role in modulating the YAP (Montrer YAP1 Anticorps)-dependent HIF1alpha (Montrer HIF1A Anticorps) pathway and shed light on the development of metabolism-targeting therapeutics for hepatocellular carcinoma chemoprevention
In lung tissues of LPS (Montrer TLR4 Anticorps)-endotoxemia, significantly increased levels of SNO (Montrer SBNO2 Anticorps)-SIRT were found. Plasma nitrite and HMGB1 levels were significantly higher than those in the sham controls.
Established a murine model of myocardial ischemia-reperfusion injury; investigated and found remote ischemic postconditioning protects against IR injury thru RAGE (Montrer AGER Anticorps)-HMGB1 Pathway.
HMGB1 promotes HAdV-7 replication and signals through TLR-4 (Montrer TLR4 Anticorps), TLR-9 (Montrer TLR9 Anticorps), and RAGE (Montrer AGER Anticorps) receptors to activate NF-kappaB (Montrer NFKB1 Anticorps), stimulating the release of inflammatory mediators and contributing to adenoviral pathology.
Silencing of Hmgb1 by specific siRNA impeded the induction of 8-Br-cAMP on prolactin (Montrer PRL Anticorps) family 8, subfamily a (Montrer CYP Anticorps), member 2 and Hmgb1 was a critical mediator of Kruppel-like factor 5 (Montrer KLF5 Anticorps) function in stromal differentiation.
In the lung, the expression of HMGB1 was greater in diet group and diet mechanical ventilation group than in control group and mechanical ventilation group.
these data suggest that HMGB1 may be a checkpoint nuclear factor of macrophage reprogramming
using Hmgb1(-/-) mice we identified the underlying mechanism as the transition of multiple quiescent stem cells from G0 to GAlert HMGB1
these results suggest that miR1423p functions as a negative regulator of neuropathic pain development through the downregulation of HMGB1, indicating that miR1423p may serve as a potential therapeutic target for neuropathic pain
HMGB1 can act as an adjuvant in modulating the bovine immune system and thus lays a foundation for using HMGB1 as an adjuvant in various bovine vaccine preparations.
Single-nucleotide polymorphism in the 3'-untranslated region of the HMGB1 gene affects the binding of target bta-miR (Montrer MYLIP Anticorps)-223 and is involved in mastitis.
The mechanisms of interaction of the non-histone chromosomal protein (Montrer HMGB2 Anticorps) HMGB1 and linker histone H1 (Montrer H1F0 Anticorps) with DNA have been studied using circular dichroism and absorption spectroscopy.
HMGB1 is able to induce considerable changes in DNA structure upon binding even when the amount of the protein directly associated with DNA is low
Interaction between non-histone chromatin protein HMGB1 and linker histone H1 (Montrer H1F0 Anticorps)
HMGB-1 might play a role in the pathological thickening of subchondral bone plate/osteophyte formation.
Analysis of mechanical response generated by binding of DNA-bending protein HMGB1 to single tethered 48.5 kb lambda-DNA molecules finds that compaction of DNA increases with increasing HMGB1 concentration.
Thrombomoduln not only binds to HMGB1 but also aids the proteolytic cleavage of HMGB1 by thrombin (Montrer F2 Anticorps).
SCARA5 (Montrer SCARA5 Anticorps) is an HMGB1 recognition receptor that is negatively involved in HMGB1-mediated inflammation in pufferfish (Tetraodon nigroviridis) and zebrafish (Danio rerio) models.
HMGB1 is a critical factor for brain development, enabling survival and proliferation of neural progenitors that will form the forebrain structures.
Systemic HMGB-1 levels were significantly elevated in both trauma groups when compared to the sham group. Haemorrhagic shock severity and duration were positively correlated with HMGB-1 levels and compared to baseline values, concentrations remained significantly increased in severe hemorrhage when compared to moderate hemorrhage.
high levels of HMGB1 in the small intestine and its relation to high levels of HMGB1 in plasma of piglets infected with E. coli O55 that suffered from infection correlated with high levels of inflammatory cytokines and bacterial translocation; levels were higher than HMGB1 levels in piglets with mild clinical symptoms
HMGB-1 may participate in the inflammatory response and liver injury in the late stage of acute liver failure
High mobility group box-1 and nucleosomes might have use as biomarkers for horses with gastrointestinal disease.
Extracellular HMGB-1 is widespread only in synovial membrane from diseased joints in horses with osteoarthritis.
Osteochondral injury was associated with a significant increase in synovial HMGB-1 concentrations in horses with joint injuries, compared with results for clinically normal horses.
Airway pressure release ventilation reduces bronchoalveolar lavage fluid HMGB1 levels and lung water, preserving oxygenation and systemic blood pressure in experimental acute respiratory distress syndrome.
heparin binding protein that facilitates neurite outgrowth
, Sulfoglucuronyl carbohydrate binding protein
, high mobility group protein 1
, high mobility group protein B1
, high-mobility group (nonhistone chromosomal) protein 1
, high-mobility group box 1
, sulfoglucuronyl carbohydrate binding protein
, high mobility group box 1
, high mobility group 1 protein
, high mobility group protein HMG1
, non-histone protein HMG1
, high mobility group protein B1-like protein
, High mobility group protein B1
, high mobility group protein B1-like
, High mobility group protein 1
, heparin-binding protein p30
, high mobility group 1