anti-Rat (Rattus) KIT anticorps pour Immunohistochemistry

Recommended KIT Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
  • C-Kit
  • CD117
  • PBT
  • SCFR
  • Bs
  • Fdc
  • Gsfsco1
  • Gsfsco5
  • Gsfsow3
  • SCO1
  • SCO5
  • SOW3
  • Ssm
  • Tr-kit
  • W
  • c-KIT
  • c-kit
  • MGF
  • KIT
  • C-KIT
  • kit
  • receptor
  • sparse
  • Xkl-1
  • kit-a
  • kit-b
  • kl1-A
  • krk1
  • pbt
  • scfr
  • KIT proto-oncogene receptor tyrosine kinase
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
  • KIT proto-oncogene receptor tyrosine kinase S homeolog
  • KIT
  • Kit
  • kita
  • kit
  • kit.S
Épitope
pTyr721
74
74
68
62
51
48
35
33
33
32
26
26
20
19
19
19
19
19
18
18
18
18
18
18
18
18
18
17
17
17
16
15
15
15
15
13
12
12
11
11
10
10
10
10
10
10
10
10
9
9
9
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
1429
594
172
45
45
38
26
22
14
5
4
4
4
4
3
1
1
1
Hôte
Lapin
1061
439
275
18
2
2
Clonalité
Polyclonal
Conjugué
Cet anticorp KIT est non-conjugé
156
142
135
118
90
76
22
18
15
13
10
10
10
10
9
8
8
8
8
8
8
7
7
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
704
698
577
363
311
174
166
124
105
84
68
38
19
13
12
10
8
6
5
4
3
3
3
3
3
2
2
2
2
1
1
Options
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N° du produit (Fournisseur)
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N° du produit ABIN6256004
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
21.991789 ABIN6260339 ELISA ICC IF IHC WB Rabbit IgG Connectez-vous pour afficher Polyclonal 0
21.991789 ABIN6255994 ELISA ICC IF IHC WB Rabbit IgG pTyr703 Connectez-vous pour afficher Polyclonal 0
18.991789 ABIN6271488 ELISA ICC IF IHC WB Rabbit IgG pTyr568 Connectez-vous pour afficher Polyclonal 0
16 ABIN6002095 IF/ICC IHC IP WB Mouse Connectez-vous pour afficher 0
11.78621 ABIN965729 IHC Rabbit pTyr721 Connectez-vous pour afficher 0
10 ABIN5662438 IHC WB Mouse Connectez-vous pour afficher 0
7 ABIN2987829 IHC WB Rabbit IgG pTyr936 Connectez-vous pour afficher Polyclonal 0
4 ABIN323546 FACS IF IHC Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN602271 IHC Rabbit IgG pTyr936 Connectez-vous pour afficher Polyclonal 0
1 ABIN2882660 IHC WB Rabbit IgG pTyr936 Connectez-vous pour afficher Polyclonal 0
1 ABIN6713339 IHC Rabbit AA 681-730 Connectez-vous pour afficher Polyclonal 0

General

Antigène Mast/stem Cell Growth Factor Receptor (KIT) Anticorps
Épitope pTyr721
(74), (74), (68), (62), (51), (48), (35), (33), (33), (32), (26), (26), (20), (19), (19), (19), (19), (19), (18), (18), (18), (18), (18), (18), (18), (18), (18), (17), (17), (17), (16), (15), (15), (15), (15), (13), (12), (12), (11), (11), (10), (10), (10), (10), (10), (10), (10), (10), (9), (9), (9), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(1429), (594), (172), (45), (45), (38), (26), (22), (14), (5), (4), (4), (4), (4), (3), (1), (1), (1)
Hôte Lapin
(1061), (439), (275), (18), (2), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp KIT est non-conjugé
(156), (142), (135), (118), (90), (76), (22), (18), (15), (13), (10), (10), (10), (10), (9), (8), (8), (8), (8), (8), (8), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(704), (698), (577), (363), (311), (174), (166), (124), (105), (84), (68), (38), (19), (13), (12), (10), (8), (6), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
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Détail du produit anti-KIT anticorps

Détail du antigène KIT Information d'application Stockage Images
Specificité Phospho-c-Kit (Tyr721) Antibody detects endogenous levels of c-Kit only when phosphorylated at Tyrosine 721
 Réactivité croisée Humain, Souris, Rat (Rattus)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogène A synthesized peptide derived from human c-Kit around the phosphorylation site of Tyrosine 721
Isotype IgG
Plasmids, Primers & others

Détail du antigène KIT

Détail du produit anti-KIT anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation c-Kit (KIT Antibody Extrait)
Sujet

Description: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.

Gene: KIT

Poids moléculaire 120,145kDa
ID gène 3815
UniProt P10721
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity

Information d'application

Détail du produit anti-KIT anticorps Détail du antigène KIT Stockage Images Haut de la page
Indications d'application WB 1:500-1:2000 IHC 1:100-1:500, IF/ICC 1:100-1:500
Restrictions For Research Use only

Stockage

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Images Haut de la page
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20 °C.Stable for 12 months from date of receipt
Date de péremption 12 months

Images

Détail du produit anti-KIT anticorps Détail du antigène KIT Information d'application Stockage Haut de la page
Images (Fournisseur)
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilize...
Western Blotting (WB) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) Western blot analysis of c-Kit phosphorylation expression in HeLa whole cell lysates,...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Human heart tissue sections by IHC-P. The tissue was fo...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Human heart tissue sections by IHC-P. The tissue was fo...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Human liver cancer tissue sections by IHC-P. The tissue...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Human liver cancer tissue sections by IHC-P. The tissue...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Human lung cancer tissue sections by IHC-P. The tissue ...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Mouse spleen tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Rat liver tissue sections by IHC-P. The tissue was form...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Rat lung tissue sections by IHC-P. The tissue was forma...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Rat ganstric tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody (ABIN6256004) ABIN6267365 at 1/200 staining Rat lung tissue sections by IHC-P. The tissue was forma...