Profil protéine

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with SMAD, Mothers Against DPP Homolog 1 (SMAD1)

• SMAD family member 1 (smad1) anticorps
• SMAD family member 1 (SMAD1) anticorps
• Mothers against dpp (Mad) anticorps
• SMAD family member 1 (Smad1) anticorps
• SMAD family member 1 L homeolog (smad1.L) anticorps

• 2/23 anticorps
• AI528653 anticorps
• apg anticorps
• BSP-1 anticorps
• BSP1 anticorps
• Afficher tous les alias de synonymes
• c28 anticorps
• CG12399 anticorps
• dMad anticorps
• Dmel\\CG12399 anticorps
• E(zen)2 anticorps
• En(vvl) anticorps
• fb39h09 anticorps
• JV4-1 anticorps
• JV41 anticorps
• l(2)k00237 anticorps
• mad anticorps
• Madh1 anticorps
• Madr1 anticorps
• Mat anticorps
• MLP anticorps
• Mlp1 anticorps
• MusMLP anticorps
• p-Mad anticorps
• pMad anticorps
• pSmad anticorps
• Smad anticorps
• smad-1 anticorps
• smad1 anticorps
• wu:fb39h09 anticorps
• wu:fb97e04 anticorps
• xmad anticorps
• Xmad1 anticorps
• Xsmad1 anticorps

Protein level used designations for SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1