anti-Humain CREB1 anticorps pour Intracellular Staining

Recommended CREB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein
  • cAMP responsive element binding protein 1 S homeolog
  • cAMP responsive element binding protein 1a
  • CREB1
  • creb1
  • CREB
  • Creb1
  • creb1.S
  • creb1a
Épitope
pSer133
135
38
38
37
22
21
16
15
12
12
8
8
7
7
6
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
551
330
299
42
39
38
36
31
27
27
19
17
15
7
7
7
2
2
1
1
1
Hôte
Souris
450
100
12
1
Clonalité
Monoclonal
Conjugué
Cet anticorp CREB1 est conjugé à/à la PE
20
17
16
7
7
6
6
6
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Intracellular Staining (ICS)
446
251
194
98
90
45
43
42
32
11
11
10
4
3
2
2
2
1
1
1
Options
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N° du produit ABIN1177047
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1177048 ICS Alexa Fluor 647 Mouse IgG1, kappa pSer133 Connectez-vous pour afficher J151-21 1
1 ABIN1177049 ICS Alexa Fluor 488 Mouse IgG1, kappa pSer133 Connectez-vous pour afficher J151-21 1

General

Antigène CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
Épitope pSer133
(135), (38), (38), (37), (22), (21), (16), (15), (12), (12), (8), (8), (7), (7), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(551), (330), (299), (42), (39), (38), (36), (31), (27), (27), (19), (17), (15), (7), (7), (7), (2), (2), (1), (1), (1)
Hôte Souris
(450), (100), (12), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp CREB1 est conjugé à/à la PE
(20), (17), (16), (7), (7), (6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Intracellular Staining (ICS)
(446), (251), (194), (98), (90), (45), (43), (42), (32), (11), (11), (10), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 référence disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-CREB1 anticorps

Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN1177047) Images
Marque BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène Phosphorylated Human CREB Peptide
Clone J151-21
Isotype IgG1, kappa

Détail du antigène CREB1

Détail du produit anti-CREB1 anticorps Information d'application Stockage References for anti-CREB1 antibody (ABIN1177047) Images Haut de la page
Antigène
Autre désignation CREB (CREB1 Antibody Extrait)
Sujet Transcription of various genes is regulated by the cyclic AMP (cAMP) signal transduction pathway through a family of cAMP Responsive Element (CRE)-Binding transcription factors that include CREB, CREM (CRE Modulator), and ATF-1 (Activating Transcription Factor 1). The genes for these transcription factors encode multiple isoforms that are created by alternative splicing, alternative initiation codons, and alternative intronic promoters. Homo- and heterodimers of these members of the basic domain-and-leucine zipper superfamily of proteins bind the palindromic TGACGTCA sequence of CRE. CREB is expressed in all somatic cells, and many different stimuli activate CREB by phosphorylation of its serine 133 (S133). The transcriptional activity and specificity of CREB are regulated by the signaling pathways initiated by the various stimuli. Transcriptional regulation by CREB family members has been implicated in many physiological responses to extracellular and environmental stimuli, such as memory, tissue growth and development, and homeostasis. The J151-21 monoclonal antibody recognizes the phosphorylated S133 of human CREB in addition to cross-reacting with S63 of human ATF-1.
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Stockage References for anti-CREB1 antibody (ABIN1177047) Images Haut de la page
Volume d'échantillon 20 μL
Restrictions For Research Use only

Stockage

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application References for anti-CREB1 antibody (ABIN1177047) Images Haut de la page
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

References for anti-CREB1 antibody (ABIN1177047)

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage Images Haut de la page
Produit citée dans:

Shaywitz, Greenberg: "CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals." dans: Annual review of biochemistry, Vol. 68, Issue 2, pp. 821-61, 2000

Images

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN1177047) Haut de la page
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (PE) (ABIN1177047) anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (PE)