TRPC4 Produits
(Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))
Catégories
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
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Catégories TRPC4 en vedette
TRPC4 Anticorps
High quality antibodies with extensive validation data.
TRPC4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TRPC4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (17)
N° du produit
ABIN571659
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN2776213
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN570934
Quantité
100 μg
Fiche technique
Fiche technique
TRPC4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6208207
Quantité
96 tests
Fiche technique
Fiche technique
TRPC4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN3130418
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
N° du produit
ABIN3130417
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN3074900
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits TRPC4
: "Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn's disease." dans: Inflammatory bowel diseases, Vol. 21, Issue 3, pp. 496-506, (2015) (PubMed).: "Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells." dans: Biochimica et biophysica acta, Vol. 1853, Issue 2, pp. 377-87, (2015) (PubMed).
: "Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 10, pp. 3653-67, (2014) (PubMed).
: "Increased expression of TRPC4 channels associated with erectile dysfunction in diabetes." dans: Andrology, Vol. 2, Issue 4, pp. 550-8, (2014) (PubMed).
: "Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility." dans: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 32941-51, (2013) (PubMed).
: "Selective G?i subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels." dans: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17029-39, (2012) (PubMed).
: "Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells." dans: American journal of physiology. Cell physiology, Vol. 303, Issue 6, pp. C635-44, (2012) (PubMed).
: "Mass spectrometric analysis of novel phosphorylation sites in the TRPC4? channel." dans: Rapid communications in mass spectrometry : RCM, Vol. 26, Issue 17, pp. 1965-70, (2012) (PubMed).
: "Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes." dans: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39171-9, (2010) (PubMed).
: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à TRPC4
transient receptor potential cation channel subfamily C member 4 (TRPC4), short transient receptor potential channel 4 (LOC100538928), transient receptor potential cation channel subfamily C member 4 (trpc4), transient receptor potential cation channel, subfamily C, member 4 (Trpc4), transient receptor potential cation channel subfamily C member 4 (Trpc4), CCE1, HTRP-4, HTRP4, STRPC4, TRP4, Trp4, TRPC4, TRPC5, Trrp4Protein level used designations for TRPC4
- transient receptor potential 4
- transient receptor potential cation channel, subfamily C, member 5
- transient receptor potential cation channel, subfamily C, member 4
- short transient receptor potential channel 4-like
- short transient receptor potential channel 4
- trp-related protein 4
- capacitative calcium entry channel Trp4
- putative capacitative calcium entry channel
- receptor-activated cation channel TRP4
- transient receptor protein 4
- CCE1
- capacitative calcium entry channel 1
- transient receptor potential channel 4
- transient receptor potential protein 4
- transient receptor potential cation channel TRPC4 middle region 2
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