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TRPC6 Produits

(Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009].

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Catégories TRPC6 en vedette

TRPC6 Anticorps

High quality antibodies with extensive validation data.

TRPC6 Kits ELISA

Reliable ELISA kits for a wide range of species.

TRPC6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TRPC6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (7)
N° du produit ABIN7441304
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN6149580
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN3044146
Quantité 100 μg
Fiche technique Fiche technique

TRPC6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960122
Quantité 96 tests
Fiche technique Fiche technique

TRPC6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323826
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3074745
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3122878
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TRPC6

Wang, Wang, Li: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." dans: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).

Alonso-González, Cabo, San José, Gago, Suazo, García-Suárez, Cobo, Vega: "Human Digital Meissner Corpuscles Display Immunoreactivity for the Multifunctional Ion Channels Trpc6 and Trpv4." dans: Anatomical record (Hoboken, N.J. : 2007), Vol. 300, Issue 6, pp. 1022-1031, (2018) (PubMed).

Wajdner, Farrington, Barnard, Peachell, Schnackenberg, Marino, Xu, Affleck, Begg, Seward: "Orai and TRPC channel characterization in FcεRI-mediated calcium signaling and mediator secretion in human mast cells." dans: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).

Álvarez-Miguel, Cidad, Pérez-García, López-López: "Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension." dans: The Journal of physiology, (2016) (PubMed).

Takada, Furuya, Sokabe: "Mechanosensitive ATP release from hemichannels and Ca²⁺ influx through TRPC6 accelerate wound closure in keratinocytes." dans: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4159-71, (2014) (PubMed).

Anderson, Kim, Hagmann, Benzing, Dryer: "Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol." dans: American journal of physiology. Cell physiology, Vol. 305, Issue 3, pp. C276-89, (2013) (PubMed).

Kim, Anderson, Wilson, Hagmann, Benzing, Dryer: "NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex." dans: American journal of physiology. Cell physiology, Vol. 305, Issue 9, pp. C960-71, (2013) (PubMed).

Li, Ding, Lopez, Takeshima, Ma, Allen, Eltit: "Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes." dans: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39171-9, (2010) (PubMed).

Ding, He, Zhou, Cheng, Yao, Lu, Cai, Jin, Dong, Xu, Wang: "Essential role of TRPC6 channels in G2/M phase transition and development of human glioma." dans: Journal of the National Cancer Institute, Vol. 102, Issue 14, pp. 1052-68, (2010) (PubMed).

Potier, Gonzalez, Motiani, Abdullaev, Bisaillon, Singer, Trebak: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à TRPC6

transient receptor potential cation channel subfamily C member 6 (TRPC6), transient receptor potential cation channel, subfamily C, member 6 (Trpc6), transient receptor potential cation channel, subfamily C, member 6a (trpc6a), transient receptor potential cation channel subfamily C member 6 (Trpc6), transient receptor potential cation channel subfamily C member 6 (trpc6), AV025995, bZ1P14.9, FSGS2, LLHWJM002, LLHWJM003, LLHWJM004, mtrp6, si:rp71-1p14.9, TRP-6, TRP6, trp6, trpc6, Trrp6

Protein level used designations for TRPC6

  • TRP-6
  • short transient receptor potential channel 6
  • transient receptor protein 6
  • calcium entry channel
  • transient receptor potential cation channel, subfamily C, member 6
  • transient receptor potential channel subfamily C member 6
  • short transient receptor potential channel 6-like
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