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IKBKB anticorps (pTyr199)

Cité dans 1 publication. Cet anticorps anti-IKBKB Polyclonal Lapin (Clone RB6996) (ABIN389574) détecte spécifiquement IKBKB dans WB. L’anticorps est réactif avec des échantillons de Humain.

The anti-Phospho-IKKb- Pab (ABIN389574 and ABIN2839600) is used in Western blot to detect Phospho-IKKb- in Y79 tissue lysate (IKBKB anticorps (pTyr199))

1 image

(1 reference)

N° du produit ABIN389574

434,77 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour IKBKB anticorps (pTyr199) (ABIN389574)

Antigène

Voir toutes IKBKB Anticorps

IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp IKBKB est non-conjugé

Application

Western Blotting (WB)

Clone

RB6996

Discover our top product IKBKB Anticorps primaire

Épitope
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pTyr199

Homologie

B, M, Rat

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This IKKb Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y199 of human IKKb.

Isotype

Ig Fraction
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 630-730) antibody
IKBKB Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (C-Term) antibody
IKBKB Reactivité: Humain WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (pTyr199) antibody
IKBKB Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody
IKBKB Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB2161 unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 3-120) antibody
IKBKB Reactivité: Humain WB, ELISA, PLA Hôte: Souris Monoclonal 1A3 unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody
IKBKB Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody
IKBKB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 3-120) antibody
IKBKB Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 3C12 unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (pTyr188) antibody
IKBKB Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody
IKBKB Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Monoclonal 3E1 unconjugated Recombinant Antibody

Indications d'application

WB: 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Zhu, Moore, Morii, Howard, Culver, Arrendale, Reddy, Evers, Zhang, Sica, Chen, Sun, Fu, Khuri, Shin, Snyder, Shoji: "Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts." dans: Current cancer drug targets, Vol. 14, Issue 4, pp. 380-93, (2014) (PubMed).
Antigène

IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

Autre désignation

IKKb

Sujet

NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the inhibitory I-kappa-B proteins by kinases (IKKa or IKKb) leads to the dissociation of the inhibitor/NF-kappa-B complex and marks the inhibitors for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs.

Poids moléculaire

86564

ID gène

3551

NCBI Accession

NP_001177649, NP_001229707, NP_001547

UniProt

O14920

Pathways

Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins