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PRKAA2 anticorps (Middle Region, Thr172)
PRKAA2
Reactivité: Humain
WB, IHC (p), EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-PRKAA2 anticorps
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Antigène
Voir toutes PRKAA2 Anticorps
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Épitope
Tous les épitopes à travers PRKAA2 Anticorps.
AA 148-177, Middle Region, Thr172
Reactivité
Toutes les réactivités sur PRKAA2 Anticorps
Humain
Hôte
Toutes les hôtes sur PRKAA2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur PRKAA2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PRKAA2 Anticorps
Cet anticorp PRKAA2 est non-conjugé
Application
Tous les applications à travers PRKAA2 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificité
This antibody reacts to PRKAA2.
Réactivité croisée (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogène
KLH conjugated synthetic peptide between 148-177 amino acids from the Central region of human PRKAA2 (Thr172)
Isotype
Ig Fraction
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Alternatives
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anti-Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2) (AA 351-450) antibody
PRKAA2
Reactivité: Humain, Souris, Rat
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur PRKAA2
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Antigène
PRKAA2
(Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
Autre désignation
PRKAA2 (PRKAA2 Produits )
Synonymes
anticorps AMPK, anticorps AMPK2, anticorps AMPKa2, anticorps PRKAA, anticorps Ampk, anticorps Ampka2, anticorps 2310008I11Rik, anticorps A830082D05, anticorps AMPKalpha2, anticorps AMPKA2, anticorps ampk, anticorps ampk2, anticorps prkaa, anticorps prkaa1, anticorps PRKAA2, anticorps protein kinase AMP-activated catalytic subunit alpha 2, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog, anticorps PRKAA2, anticorps Prkaa2, anticorps prkaa2.S, anticorps prkaa2
Sujet
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK alpha-2 chain, AMPK2
Poids moléculaire
62320 Da
ID gène
5563
NCBI Accession
NP_006243
Pathways
AMPK Signaling , Carbohydrate Homeostasis , Chromatin Binding , Regulation of Carbohydrate Metabolic Process , L'effet Warburg
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