Aperçu des produits pour anti-NCOA1 (NCOA1) Anticorps

Full name:
anti-Nuclear Receptor Coactivator 1 Anticorps (NCOA1)
Chez www.anticorps-enligne.fr sont 121 Nuclear Receptor Coactivator 1 (NCOA1) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions NCOA1 Protéines (9) et NCOA1 Kits (6) et beaucoup plus de produits pour cette protéine. Un total de 140 NCOA1 produits sont actuellement listés.
Synonymes:
bHLHe42, bHLHe74, c-src, C-src1, CG7524, csrc, D-src, D-Src64B, DKFZp459C083, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, F-SRC-1, HD-358, KAT13A, MGC128615, MRE5, NCOA1, pp60c-src, pp60v-src, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRA1, src, src-1, src1, src2, src64, SRC 64B, src64b, xsrc, zgc:86613
afficher tous les anticorps Gène GeneID UniProt
NCOA1 8648 Q15788
NCOA1 17977 P70365
NCOA1 313929  

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anti-NCOA1 Anticorps mieux référencés

  1. Human Polyclonal NCOA1 Primary Antibody pour EIA, WB - ABIN358229 : Encinas, Crowder, Milbrandt, Johnson: Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. dans The Journal of biological chemistry 2004 (PubMed)
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  2. Human Polyclonal NCOA1 Primary Antibody pour IHC (p), WB - ABIN197376 : Parker, Mardon, Lebo, Varmus, Bishop: Isolation of duplicated human c-src genes located on chromosomes 1 and 20. dans Molecular and cellular biology 1985 (PubMed)
    Show all 4 references for 197376

  3. Human Polyclonal NCOA1 Primary Antibody pour EIA, IHC (p) - ABIN359992 : Lopez, Carron, Ghysdael: v-SRC specifically regulates the nucleo-cytoplasmic delocalization of the major isoform of TEL (ETV6). dans The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for 359992

  4. Human Polyclonal NCOA1 Primary Antibody pour IHC (p), WB - ABIN196876 : Pyper, Bolen: Identification of a novel neuronal C-SRC exon expressed in human brain. dans Molecular and cellular biology 1990 (PubMed)
    Show all 4 references for 196876

  5. Human Monoclonal NCOA1 Primary Antibody pour BI, WB - ABIN968842 : Oñate, Tsai, Tsai, OMalley: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. dans Science (New York, N.Y.) 1995 (PubMed)
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  6. Amphibian Polyclonal NCOA1 Primary Antibody pour FACS, ICC - ABIN152700 : Rogatsky, Zarember, Yamamoto: Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. dans The EMBO journal 2001 (PubMed)
    Show all 3 references for 152700

  7. Human Polyclonal NCOA1 Primary Antibody pour EIA, WB - ABIN953617 : Son, Lee: Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers. dans FEBS letters 2010 (PubMed)
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  8. Human Polyclonal NCOA1 Primary Antibody pour WB - ABIN151779 : Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: Androgen modulation of coregulator expression in prostate cancer cells. dans Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

  9. Human Polyclonal NCOA1 Primary Antibody pour EIA, IHC (p) - ABIN358230 : Varrin-Doyer, Vincent, Cavagna, Auvergnon, Noraz, Rogemond, Honnorat, Moradi-Améli, Giraudon: Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. dans The Journal of biological chemistry 2009 (PubMed)

  10. Cow (Bovine) Polyclonal NCOA1 Primary Antibody pour WB - ABIN2778219 : Lavery, McEwan: Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a. dans Biochemistry 2008 (PubMed)

Plus d’anticorps contre NCOA1 partenaires d’interaction

Xenopus laevis Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. The structural and functional competency of the UPIII (Montrer UPK3A Anticorps)-Src (Montrer SRC Anticorps) signaling system in membrane microdomains is strictly regulated during oocyte maturation.

Human Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. miR (Montrer MLXIP Anticorps)-4443 acts in a tumor-suppressive manner by down-regulating TRAF4 (Montrer TRAF4 Anticorps) and NCOA1 downstream of MEK (Montrer MAP2K1 Anticorps)-C/EBP (Montrer CEBPA Anticorps)-mediated leptin (Montrer LEP Anticorps) and insulin (Montrer INS Anticorps) signaling, and that insulin (Montrer INS Anticorps) and/or leptin (Montrer LEP Anticorps) resistance (e.g. in obesity) may suppress this pathway and increase the risk of metastatic CRC (Montrer CALR Anticorps).

  2. Results provide the first evidence that NCOA1 is a direct target of miR (Montrer MLXIP Anticorps)-105-1 suggesting that NCOA1 and miR (Montrer MLXIP Anticorps)-105-1 may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of HCC (Montrer FAM126A Anticorps) patients.

  3. Data suggest that steroid receptor (Montrer ESR2 Anticorps) coactivators (NCOA1, NCOA2 (Montrer NCOA2 Anticorps), NCOA3 (Montrer NCOA3 Anticorps)) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (Montrer ESR2 Anticorps) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]

  4. The mechanism of IL-6-induced AR activation is mediated through enhancing AR-SRC-1 interaction and inhibiting AR-SMRT interaction.

  5. IL-6-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 and SMRT to the AR in a ligand-independent manner

  6. NCOA1 potentiates breast cancer angiogenesis through upregulating HIF1alpha (Montrer HIF1A Anticorps) and AP-1 (Montrer FOSB Anticorps)-mediated VEGFa (Montrer VEGFA Anticorps) expression

  7. miR (Montrer MLXIP Anticorps)-137 has a role in targeting p160 (Montrer MSH6 Anticorps) steroid receptor (Montrer ESR2 Anticorps) coactivators SRC1 (Montrer SRC Anticorps), SRC2 (Montrer NCOA2 Anticorps), and SRC3 (Montrer NCOA3 Anticorps) and inhibits cell proliferation

  8. Report novel PAX3 (Montrer PAX3 Anticorps)-NCOA1 gene fusions in biphenotypic sinonasal sarcomas with focal rhabdomyoblastic differentiation.

  9. Data indicate that finerenone inhibits mineralocorticoid receptor (Montrer NR3C2 Anticorps) (MR), steroid receptor coactivator-1 binding at the regulatory sequence.

  10. Data suggest that over-stimulating the steroid seceptor coactivators SRC-1 (Montrer SRC Anticorps), SRC-2 (Montrer NCOA2 Anticorps), and SRC-3 (Montrer NCOA3 Anticorps) oncogenic program can be an effective strategy to kill cancer cells.

Mouse (Murine) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. The results suggest that biochanin A activates RORgamma-dependent IL-17 (Montrer IL17A Anticorps) transcription through the enhancement of STAT3 (Montrer STAT3 Anticorps) phosphorylation and STAT3 (Montrer STAT3 Anticorps)-mediated recruitment of NCOA1 to RORgamma.

  2. ubiquitination of K446 limits RORgammat-mediated Th17 differentiation by inhibiting the recruitment of coactivator SRC1

  3. Loss of SRC-1 is associated with high Blood Pressure and Aortic Stiffness.

  4. local E2 inhibition could induce aberrant actin polymerization and also showed an important role of SRC-1 in the mediation of local E2 action on hippocampal synaptic plasticity by regulation of actin cytoskeleton dynamics

  5. SRC-1/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (Montrer SLC12A3 Anticorps)-like abnormalities in the hearts of newborn and adult mice.

  6. While hippocampal SRC-1 was significantly downregulated by orchidectomy (ORX), its expression was rescued by treatment with testosterone in a dose-dependent manner. Testosterone regulates synaptic proteins involves AR, estrogen receptors and SRC-1.

  7. fetal lungs produce signals to initiate labor when mature, and SRC-1/-2-dependent production of SP-A (Montrer SFTPA1 Anticorps) and PAF (Montrer KIAA0101 Anticorps) is crucial for this process

  8. Consequently, SRC-1 null mice displayed low TAT (Montrer TAT Anticorps) expression and presented with hypertyrosinemia and corneal alterations, 2 clinical features observed in the human syndrome of TAT (Montrer TAT Anticorps) deficiency.

  9. the effect of orchidectomy (ORX) on the expression of SRC-1

  10. Letrozole induces dramatic decrease of SRC-1 in the medial septal, hippocampus, medial habenular nucleus, arcuate hypothalamic nucleus and superior colliculus.

Pig (Porcine) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. we cloned and sequenced full length cDNA of NCOA-1 gene in pig. The putative protein includes 1440 amino acids. Sequences alignment showed that pig NCOA-1 gene cDNA sequence has identity of 93.73% with human and mouse.

Fruit Fly (Drosophila melanogaster) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src (Montrer SRC Anticorps) in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (Montrer TMOD4 Anticorps) (CP) alphabeta heterodimer, which regulates actin (Montrer ACTB Anticorps) filament (F-actin (Montrer ACTB Anticorps)) polymerization, limits Src (Montrer SRC Anticorps)-induced apoptosis or tissue overgrowth by restricting JNK (Montrer MAPK8 Anticorps) activation.

  6. Dumbfounded/Neph1 (Montrer NEPH1 Anticorps), a key diaphragm constituent, is a target of the Src kinase (Montrer CSK Anticorps) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (Montrer NEPH1 Anticorps) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src (Montrer SRC Anticorps) family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A (Montrer PPP2R2B Anticorps)- and Src (Montrer SRC Anticorps)-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (Montrer ACTB Anticorps) formation and Jun kinase (Montrer MAPK9 Anticorps) activation in plasmatocytes.

NCOA1 profil antigène

Antigen Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with NCOA1

  • nuclear receptor coactivator 1 (NCOA1) anticorps
  • nuclear receptor coactivator 1 (ncoa1) anticorps
  • steroid receptor RNA activator 1 (sra1) anticorps
  • steroid receptor RNA activator 1 (SRA1) anticorps
  • steroid receptor RNA activator 1 (LOC100345921) anticorps
  • nuclear receptor coactivator 1 (Ncoa1) anticorps
  • Src oncogene at 64B (Src64B) anticorps
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (src-b) anticorps
  • bHLHe42 anticorps
  • bHLHe74 anticorps
  • c-src anticorps
  • C-src1 anticorps
  • CG7524 anticorps
  • csrc anticorps
  • D-src anticorps
  • D-Src64B anticorps
  • DKFZp459C083 anticorps
  • Dmel\CG7524 anticorps
  • DmHD-358 anticorps
  • Dm SRC1 anticorps
  • dsrc anticorps
  • Dsrc64 anticorps
  • Dsrc64B anticorps
  • F-SRC-1 anticorps
  • HD-358 anticorps
  • KAT13A anticorps
  • MGC128615 anticorps
  • MRE5 anticorps
  • NCOA1 anticorps
  • pp60c-src anticorps
  • pp60v-src anticorps
  • RIP160 anticorps
  • si:dkey-5g7.6 anticorps
  • si:dkey-34f16.6 anticorps
  • SRA1 anticorps
  • src anticorps
  • src-1 anticorps
  • src1 anticorps
  • src2 anticorps
  • src64 anticorps
  • SRC 64B anticorps
  • src64b anticorps
  • xsrc anticorps
  • zgc:86613 anticorps

Protein level used designations for NCOA1

nuclear receptor coactivator 1 , DKEY-34F16.7 , SRC1 , steroid receptor RNA activator 1 , Hin-2 protein , PAX3/NCOA1 fusion protein , class E basic helix-loop-helix protein 74 , renal carcinoma antigen NY-REN-52 , steroid receptor coactivator-1 , NCoA-1 , SRC-a/NCoA-1 , mNRC-1 , nuclear receptor coactivator protein 1 , steroid receptor coactivator 1 , SRC-1 , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , p60-Src-2 , tyrosine protein kinase pp60-c-src , tyrosine-protein kinase Src-2 , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

GENE ID SPECIES
422016 Gallus gallus
563288 Danio rerio
459068 Pan troglodytes
100025270 Monodelphis domestica
100385756 Callithrix jacchus
100471908 Ailuropoda melanoleuca
100556605 Anolis carolinensis
415137 Danio rerio
606944 Canis lupus familiaris
780787 Bos taurus
100049723 Xenopus laevis
100135196 Xenopus (Silurana) tropicalis
100173951 Pongo abelii
100345921 Oryctolagus cuniculus
8648 Homo sapiens
17977 Mus musculus
313929 Rattus norvegicus
574068 Sus scrofa
48973 Drosophila melanogaster
380430 Xenopus laevis
475684 Canis lupus familiaris
525346 Bos taurus
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