anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

• ATP binding cassette subfamily B member 1 (ABCB1) anticorps
• ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
• ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps

• ABC20 anticorps
• Abcb1 anticorps
• CD243 anticorps
• CLCS anticorps
• GP170 anticorps
• Afficher tous les alias de synonymes
• mdr anticorps
• Mdr1 anticorps
• Mdr1b anticorps
• P-GP anticorps
• Pgy-1 anticorps
• Pgy1 anticorps

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1