anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Anticorps

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps sur anticorps-enligne.fr

Showing 10 out of 31 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 3 to 7 Days
$318.45
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Connectez-vous pour afficher 11 to 16 Days
$438.96
Détails
Humain Souris Inconjugué IF, IP, WB   100 μL Connectez-vous pour afficher 16 Days
$405.08
Détails
Humain Souris Inconjugué IC, FACS, IHC, WB   250 μg Connectez-vous pour afficher 11 to 16 Days
$771.57
Détails
Humain Rat Inconjugué IC, FACS, IHC, WB   125 μg Connectez-vous pour afficher 11 to 16 Days
$795.14
Détails
Humain Souris Inconjugué IC, FACS, IHC, WB   125 μg Connectez-vous pour afficher 11 to 16 Days
$807.71
Détails
Humain Souris Inconjugué WB   100 μL Connectez-vous pour afficher 11 to 16 Days
$570.43
Détails
Humain Souris Inconjugué IC, FACS, IP, IHC, WB   100 μg Connectez-vous pour afficher 11 to 16 Days
$672.57
Détails
Humain Souris Inconjugué IC, FACS, IP   1 mL Connectez-vous pour afficher 11 to 16 Days
$707.14
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB   500 μL Connectez-vous pour afficher 11 to 16 Days
$689.86
Détails

ABCB1B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps mieux référencés

  1. Human Polyclonal ABCB1B Primary Antibody pour FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. dans Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B partenaires d’interaction

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Results show that CD133 and MDR1 (Montrer TBC1D9 Anticorps) expression increase in recurrent pediatric pilocytic astrocytomas (PAs (Montrer PASK Anticorps)) following chemotherapy, and in drug resistant tumor cells. CD133 regulates MDR1 (Montrer TBC1D9 Anticorps) expression via the PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) signaling. These results provide evidence that CD133 contributes to multidrug resistance by regulating MDR1 (Montrer TBC1D9 Anticorps) levels via the PI3K (Montrer PIK3CA Anticorps)-Akt (Montrer AKT1 Anticorps)-NF-kappaB (Montrer NFKB1 Anticorps) signal pathway.

  2. PG accumulation assay is a new, unique tool for the parallel determination of the function of the ABCG2 (Montrer ABCG2 Anticorps), ABCB1 (Montrer ABCB1 Anticorps), and ABCC1 (Montrer ABCC1 Anticorps) multidrug transporters

  3. Abcb1a (Montrer ABCB1 Anticorps)/b(-/-);Abcg2 (Montrer ABCG2 Anticorps)(-/-) mice revealed increased brain penetration of rapamycin (13-fold), AZD8055 (7.7-fold), and NVP-BEZ235 (4.5-fold), but not ZSTK474 relative to WT mice. Importantly, ABC (Montrer ABCB6 Anticorps) transporters limited rapamycin brain penetration to subtherapeutic levels, while the reduction in NVP-BEZ235 brain penetration did not prevent target inhibition.

  4. ABCB1 (Montrer ABCB1 Anticorps) genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  5. High MDR1 (Montrer TBC1D9 Anticorps) expression is associated with multidrug resistance in breast cancer.

  6. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (Montrer CD44 Anticorps), ABCB1 (Montrer ABCB1 Anticorps) and ADAM17 (Montrer ADAM17 Anticorps)

  7. The T-allele of ABCB1 (Montrer ABCB1 Anticorps)-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (Montrer ERBB2 Anticorps)-positive Breast Cancer patients.

  8. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (Montrer ABCB4 Anticorps)--{REVIEW}

  9. Studied ABCB1 (Montrer ABCB1 Anticorps) protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1 (Montrer ABCB1 Anticorps)-expressing neurons in the left habenula.

  10. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (Montrer ABCC6 Anticorps), ABCB1 (Montrer ABCB1 Anticorps) and CYP2C8 (Montrer CYP2C8 Anticorps) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (Montrer ABCB4 Anticorps), multi-drug resistance protein, MDR1 (Montrer ABCB4 Anticorps)).Drugs with ER < 1 (Montrer MIER1 Anticorps) almost do not bind the main binding cavity (MBC (Montrer CACNA1C Anticorps)) of P-gp (Montrer ABCB4 Anticorps).

  2. conclusion, MDR1 (Montrer ABCB4 Anticorps) and BCRP (Montrer ABCG2 Anticorps) are expressed on apical membranes of the rodent placental SynT (Montrer STX1A Anticorps)-II layer.

  3. Mdr1 (Montrer ABCB4 Anticorps) enforces T Cell homeostasis in the presence of intestinal bile acids.

  4. Loss of ABCB1 (Montrer ABCB1 Anticorps) expression is associated with neonatal hyperbilirubinemia.

  5. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Anticorps) ATPase (Montrer DNAH8 Anticorps) activity

  6. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  7. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Anticorps) activity and reverse the up-regulated P-gp (Montrer ABCB4 Anticorps) and MDR1 (Montrer ABCB4 Anticorps) levels induced by artemisinin.

  8. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Anticorps) gene expression and activity in an enantiomer-specific way.

  9. Pgp (Montrer ABCB4 Anticorps)-coupled ATPase (Montrer DNAH8 Anticorps) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  10. Data show that human transgenic mutant huntingtin (Montrer HTT Anticorps) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Anticorps)) which suggests that MDR1 (Montrer ABCB4 Anticorps) might be a potential therapeutic target for Huntington's disease.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP binding cassette subfamily B member 1 (ABCB1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ABC20 anticorps
  • Abcb1 anticorps
  • CD243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • mdr anticorps
  • Mdr1 anticorps
  • Mdr1b anticorps
  • P-GP anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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