anti-Chloride Channel 5 (CLCN5) Anticorps

CLCN5 encodes a member of the ClC family of chloride ion channels and ion transporters. De plus, nous expédions Chloride Channel 5 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CLCN5 12728 Q9WVD4
CLCN5 1184 P51795
CLCN5 25749 P51796
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Top anti-Chloride Channel 5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 64 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-Clcn5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Mouse Brain Host:  Rabbit  Target Name:  Clcn5  Sample Type:  Rat Lung  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: CLCN5 Antibody [NBP1-84451] - Staining of human cerebral cortex shows moderate granular positivity in neuronal cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué WB WB Image Sample(30 μg of whole cell lysate) A:A431, 7.5% SDS PAGE antibody diluted at 1:500 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Humain Lapin Inconjugué ICC, IF, WB Western Blot: CLCN5 Antibody  - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue. Immunocytochemistry/Immunofluorescence: CLCN5 Antibody  - Staining of human cell line RH-30 shows localization to cytosol & the Golgi apparatus. 100 μL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB CLCN5 Antibody (N-term) (ABIN1881207) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the CLCN5 antibody detected the CLCN5 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB Western Blot: CLCN5 Antibody [NBP1-69123] - Sample Type: Mouse Heart Antibody Dilution: 1.0ug/ml Western Blot: CLCN5 Antibody [NBP1-69123] - Sample Type: Mouse Kidney Antibody Dilution: 1.0ug/ml 100 μL Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Humain Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$334.77
Détails
Humain Lapin Inconjugué IHC, ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué IF/ICC, WB Western blot analysis of extracts of various cell lines, using CLCN5 antibody (ABIN5973337) at 1/1000 dilution. 100 μL Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails

anti-Chloride Channel 5 Anticorps mieux référencés

  1. Human Polyclonal Chloride Channel 5 Primary Antibody pour WB - ABIN1881207 : White: On the position and value of those Lesions of the Brain which cause a rise of Temperature. dans The Journal of physiology 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Chloride Channel 5 Primary Antibody pour IHC, IHC (p) - ABIN4299055 : Ceol, Tiralongo, Baelde, Vianello, Betto, Marangelli, Bonfante, Valente, Della Barbera, DAngelo, Anglani, Del Prete: Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies. dans PLoS ONE 2012 (PubMed)

Plus d’anticorps contre Chloride Channel 5 partenaires d’interaction

Xenopus laevis Chloride Channel 5 (CLCN5) interaction partners

  1. analysis of extracellular determinants of anion discrimination of the Cl-/H+ antiporter protein CLC-5

Mouse (Murine) Chloride Channel 5 (CLCN5) interaction partners

  1. This study demonistrated that Clcn5 gene expression in mouse dorsal raphe nucleus

  2. ClC-5 plays an essential role in exocytosis of NHE3 (Montrer SLC9A3 Anticorps).

  3. HNF1alpha (Montrer HNF1A Anticorps) directly regulates the expression of ClC-5 in the renal proximal tubule

  4. ClC-5 is unique among CLC (Montrer CLC Anticorps) proteins in being crucial for proximal tubular endocytosis and the PY-motif-dependent ubiquitylation of ClC-5 is dispensable for this rol

  5. findings show that endosomal chloride concentration, which is raised by ClC-5 in exchange for protons accumulated by H+-ATPase (Montrer ATP6AP1 Anticorps), may play a role in endocytosis

  6. Our studies demonstrate a role for CLC-5 in the immunopathogenesis of ulcerative colitis

  7. ClC-5 regulates dentin development through TGF-beta1 (Montrer TGFB1 Anticorps) pathway

  8. Disruption of CLC-5 expression causes abnormal calcium crystal agglomeration on the surface of kidney collecting duct cells.

  9. hypercalciuria in the ClC-5 KO mice on low and high calcium diets is of bone and renal origin and is not caused by increased intestinal calcium absorption

  10. Impaired protein endocytosis caused by invalidation of ClC-5 primarily reflects a trafficking defect of megalin (Montrer LRP2 Anticorps) and cubilin (Montrer CUBN Anticorps) in PTC (Montrer PTCH1 Anticorps).

Human Chloride Channel 5 (CLCN5) interaction partners

  1. We demonstrated that most Polish patients with DD carry CLCN5 mutations, and they usually present with proteinuria and hypercalciuria.

  2. Novel CLCN5 (c.1205G>A, p.W402*) and FGF23 (Montrer FGF23 Anticorps) (c.526C>G, p.R176G) mutations were found in two patients from the remaining two families

  3. Expression of ClC-5 carrying Dent's disease-associated mutations in HEK293 cells had varying effects: (1) no detectable expression of mutant protein; (2) retention of a truncated protein in the endoplasmic reticulum; or (3) diminished protein expression with normal distribution in early endosomes.

  4. These data suggest that ClC-5 enhances the cytotoxic action of Clostridium difficile toxins TcdA and TcdB by accelerating the acidification and maturation of vesicles of the early and early-to-late endosomal system.

  5. A diagnosis of Dent disease was established in 19 boys from 16 families by the presence of loss of function/deleterious mutations in CLCN5 or OCRL1 (Montrer OCRL Anticorps).

  6. we carefully investigated the functional effects of four CLC-5 mutations, including three missense mutations (S244L, R345W, T657S) and one nonsense mutation (Q629X)

  7. A novel mutation in the CLCN5 gene was identified in our patient with Dent's disease.

  8. structural complexity of the CLCN5 5'UTR (Montrer UTS2R Anticorps) region

  9. ATP induces conformational changes in the carboxyl-terminal region of ClC-5.

  10. study described a single Chinese family with Dent disease, and findings suggest that a novel frameshift mutation (c. 246delG) in exon 5 of the CLCN5 gene was responsible for Dent disease in this case

Chloride Channel 5 (CLCN5) profil antigène

Profil protéine

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CLCN5

  • chloride voltage-gated channel 5 (CLCN5) anticorps
  • chloride channel, voltage-sensitive 5 L homeolog (clcn5.L) anticorps
  • chloride channel, voltage-sensitive 5 (clcn5) anticorps
  • chloride channel, voltage-sensitive 5 (Clcn5) anticorps
  • chloride voltage-gated channel 5 (Clcn5) anticorps
  • 5430408K11Rik anticorps
  • ClC-5 anticorps
  • CLC5 anticorps
  • CLCK2 anticorps
  • CLCN3 anticorps
  • CLCN4 anticorps
  • Clcn5 anticorps
  • clcn5-A anticorps
  • D930009B12Rik anticorps
  • DENTS anticorps
  • DKFZp469O2315 anticorps
  • DXImx42e anticorps
  • hCIC-K2 anticorps
  • NPHL1 anticorps
  • NPHL2 anticorps
  • Sfc13 anticorps
  • T25545 anticorps
  • XLRH anticorps
  • XRN anticorps

Protein level used designations for CLCN5

chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease) , chloride channel protein 5 , chloride channel 5 , H(+)/Cl(-) exchange transporter 5-like , Chloride channel protein 5 , H(+)/Cl(-) exchange transporter 5 , chloride transporter ClC-5 , voltage-gated chloride ion channel CLCN5 , clC-5 , chloride channel CLC-5 , chloride channel CLCN5 , chloride channel Clc-5

GENE ID SPECIES
493644 Bos taurus
422285 Gallus gallus
491882 Canis lupus familiaris
394306 Xenopus laevis
694497 Macaca mulatta
734069 Xenopus (Silurana) tropicalis
100410688 Callithrix jacchus
100174406 Pongo abelii
100581324 Nomascus leucogenys
12728 Mus musculus
1184 Homo sapiens
25749 Rattus norvegicus
100008741 Oryctolagus cuniculus
100135502 Cavia porcellus
397263 Sus scrofa
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