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Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. De plus, nous expédions GDNF Family Receptor alpha 1 Protéines (25) et GDNF Family Receptor alpha 1 Kits (23) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal GFRA1 Primary Antibody pour IHC (p), WB - ABIN2473776
Treanor, Goodman, de Sauvage, Stone, Poulsen, Beck, Gray, Armanini, Pollock, Hefti, Phillips, Goddard, Moore, Buj-Bello, Davies, Asai, Takahashi, Vandlen, Henderson, Rosenthal: Characterization of a multicomponent receptor for GDNF. dans Nature 1996
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Human Polyclonal GFRA1 Primary Antibody pour IHC, ELISA - ABIN1002344
Sanicola, Hession, Worley, Carmillo, Ehrenfels, Walus, Robinson, Jaworski, Wei, Tizard, Whitty, Pepinsky, Cate: Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. dans Proceedings of the National Academy of Sciences of the United States of America 1997
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Human Polyclonal GFRA1 Primary Antibody pour IF (p), IHC (p) - ABIN726230
Ma, Zhou, Li, Zheng, Wu, Niu, Tang, He, Li, Hua: Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT. dans Scientific reports 2016
Human Polyclonal GFRA1 Primary Antibody pour IF (p) - ABIN726234
Li, Bhave, Chow, Riera, Schlee, Rauch, Atanasova, Cate, Whitty: Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels. dans The Journal of biological chemistry 2015
GFRA1 regulates AMPK (Montrer PRKAA1 Anticorps)-dependent autophagy by promoting SRC (Montrer SRC Anticorps) phosphorylation independent of proto-oncogene (Montrer RAB1A Anticorps) RET (Montrer RET Anticorps) kinase
RET (Montrer RET Anticorps) c.1296A may be a common susceptibility allele for nephron underdosing-related diseases. The 5'-UTR (Montrer UTS2R Anticorps) and intronic variants near exon 5 of GFRA1 are not associated with nephron endowment.
Hox (Montrer MSH2 Anticorps) proteins coordinate motor neuron differentiation and connectivity programs through Ret (Montrer RET Anticorps)/Gfra genes.
This study demonstrate, using a knock-in mouse model in which GFRalpha1 is no longer located in lipid rafts, that the developmental functions of GDNF in the periphery require the translocation of the GDNF receptor complex into lipid rafts.
Methylation changes of GFRA1, SRF, and ZNF382 (Montrer ZNF382 Anticorps) may be a potential biomarker set for prediction of gastric carcinoma metastasis.
GFRalpha1 levels in neurons from autopsied AD brains are significantly decreased.
These findings collectively demonstrate that GFRalpha1 released by nerves enhances perineural invasion through GDNF-RET (Montrer RET Anticorps) signaling and that GFRalpha1 expression by cancer cells enhances but is not required for it.
The study shows co-localization of RET (Montrer RET Anticorps) with GFRA1 and GFRA2 (Montrer GFRA2 Anticorps) in myenteric ganglia of the adult human colon.
The expression of GFRalpha1 and/or GFRalpha3 (Montrer GFRA3 Anticorps), especially when combined with ARTN (Montrer ARTN Anticorps) expression, may be useful predictors of disease progression and outcome in specific subtypes of mammary carcinoma.
Mutations in GFRA1 gene is associated with urinary tract malformations.
the neural cell adhesion molecule NCAM (Montrer NCAM1 Anticorps) is co-expressed and directly interacts with GFRalpha1 in embryonic Purkinje cells.
The GDNF-GFRalpha1 complex is essential for proper hippocampal circuit development.
GDNF signals were able to induce the stratified aggregate formation of GFRalpha1-positive undifferentiated spermatogonia
LncRNA033862 is an antisense transcript of the GDNF receptor alpha1 (Gfra1) that lacks protein coding potential and regulates Gfra1 expression levels by interacting with Gfra1 chromatin.
Gfra1 expression in the urinary tract strictly depends on cell-type and specific stage in kidney development.
SorLA (Montrer SORL1 Anticorps) acts as sorting receptor for the GDNF/GFRalpha1 complex, directing it from the cell surface to endosomes.
our data demonstrate that RET (Montrer RET Anticorps)/GFRalpha signals are dispensable for thymic T cell development in vivo
GFRalpha1 is critical for the development and function of the main olfactory system, contributing to the development and allocation of all major classes of neurons and glial cells.
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
GDNF family receptor alpha 1
, GDNF family receptor alpha-1
, GDNF family receptor alpha-1-like
, GDNF receptor alpha-1
, GPI-linked anchor protein
, Glial cell line-derived neurotrophic factor receptor alpha
, PI-linked cell-surface accessory protein
, RET ligand 1
, TGF-beta related neurotrophic factor receptor 1
, TGF-beta-related neurotrophic factor receptor 1
, GDNF receptor alpha
, glial cell line derived neurotrophic factor family receptor alpha 1
, GFR alpha-1