Laminin, gamma 2 (LAMC2) Kits ELISA

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. De plus, nous expédions LAMC2 Anticorps (55) et LAMC2 Protéines (10) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
LAMC2 3918 Q13753
LAMC2 16782  
Anti-Rat LAMC2 LAMC2 192362  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne

Top LAMC2 Kits ELISA sur

Showing 2 out of 10 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 6.7 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
  96 Tests Connectez-vous pour afficher 15 to 18 Days

LAMC2 Kits ELISA mieux référencés

  1. Human LAMC2 Kit ELISA pour Sandwich ELISA - ABIN417810 : Kosanam, Prassas, Chrystoja, Soleas, Chan, Dimitromanolakis, Blasutig, Rückert, Gruetzmann, Pilarsky, Maekawa, Brand, Diamandis: Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues. dans Molecular & cellular proteomics : MCP 2013 (PubMed)
    Show all 4 Pubmed References

Plus Kits ELISA pour LAMC2 partenaires d'interaction

Human Laminin, gamma 2 (LAMC2) interaction partners

  1. Study found that high expression of LAMC2 was significantly associated with shorter disease-free survival in GC and, that expression of LAMC2 was significantly upregulated when PCDH8 was overexpressed.

  2. The results of this study highlight the value of LAMC2 as a marker of cancer invasion. LAMC2-positive foci in leukoplakia suggest an imminent risk of cancer.

  3. Results indicate that LAMC2-Dox mice expressing the human protein are unable to sustain structuring of a proper basement membrane (BM) at the interface between ameloblasts and maturing enamel. This failure may be related to the atypical composition of the BM in the maturation stage and reaffirms that the atypical BM is essential for enamel maturation.

  4. Overexpression of LAMC2 and knockdown of CD82 (Montrer CD82 Kits ELISA) markedly promoted GC cell invasion and activated EGFR (Montrer EGFR Kits ELISA)/ERK1/2 (Montrer MAPK1/3 Kits ELISA)-MMP7 (Montrer MMP7 Kits ELISA) signaling via upregulation of the expression of phosphorylated (p)-EGFR (Montrer EGFR Kits ELISA), p-ERK1/2 (Montrer MAPK1/3 Kits ELISA) and MMP7 (Montrer MMP7 Kits ELISA).

  5. The data presented provide a novel insight into how CDX2 (Montrer CDX2 Kits ELISA) is implicated in the transcriptional regulation of LAMC2 in intestinal epithelial cells, a function that is impaired during mucosal inflammation where a high level of TNF-alpha (Montrer TNF Kits ELISA) is present.

  6. Seventeen percent of the patients were compound heterozygous or homozygous for mutations in the gene LAMA3 (Montrer LAMA3 Kits ELISA), 59% carried mutations in both alleles of LAMB3 (Montrer LAMB3 Kits ELISA), and 12% were homozygous for mutations in LAMC2. In nine patients with severe generalized JEB, detection of two mutations in one of the genes LAMA3 (Montrer LAMA3 Kits ELISA), LAMB3 (Montrer LAMB3 Kits ELISA), or LAMC2 was not possible, so the molecular basis of disease could not be clarified completely

  7. Laminin expression depends on Ecad (Montrer CDH1 Kits ELISA) loss and allows Ecad (Montrer CDH1 Kits ELISA)-defective gastric cancer cells to survive and invade.

  8. Data suggest that LAMC2 promotes metastasis in lung adenocarcinoma via EMT (Montrer ITK Kits ELISA) and may be a potential therapeutic target.

  9. LAMC2 is a novel non-small cell lung cancer prognostic factor.

  10. Diagnostic value of p40 (Montrer IL9 Kits ELISA) and LN332 in metaplastic spindle cell carcinoma of the breast was found to be less than that of routinely used markers (p63 (Montrer RPE65 Kits ELISA) and cytokeratins). LN332 showed staining in a significant proportion of phyllodes tumours and sarcomas.

Mouse (Murine) Laminin, gamma 2 (LAMC2) interaction partners

  1. Data suggest that LAMC2 promotes metastasis in lung adenocarcinoma via EMT (Montrer ITK Kits ELISA) and may be a potential therapeutic target.

  2. Periostin (Montrer POSTN Kits ELISA) was associated with laminin gamma2, and this association enhanced the proteolytic cleavage of the laminin gamma2 long form to produce its short form.

  3. short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin, nidogen-1 (Montrer NID1 Kits ELISA), fibulin-1 (Montrer FBLN1 Kits ELISA) and fibulin-2 (Montrer FBLN2 Kits ELISA)

  4. Thymosin beta(4 (Montrer TMSB4X Kits ELISA)) stimulates Lamc2 production independent of TGF-beta (Montrer TGFB1 Kits ELISA).

  5. agrin (Montrer AGRN Kits ELISA) and perlecan (Montrer HSPG2 Kits ELISA) cluster with laminin-2 to contribute to assembly of aneural AChR clusters that precede neural agrin (Montrer AGRN Kits ELISA) release as well as affect later NMJ development

  6. Protein production was in excess of the amount required to form heterotrimeric laminin-332 and was associated with the migrating epithelial sheet, suggesting a potential role in wound healing for monomeric laminin-gamma2.

  7. Laminin gamma2 mediates Wnt5a (Montrer WNT5A Kits ELISA)-induced invasion of gastric cancer cells.

LAMC2 profil antigène

Antigen Summary

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain\; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature.

Gene names and symbols associated with Laminin, gamma 2 (LAMC2) Kits ELISA

  • laminin subunit gamma 2 (LAMC2) anticorps
  • laminin, gamma 2 (Lamc2) anticorps
  • laminin subunit gamma 2 (Lamc2) anticorps
  • AA589349 anticorps
  • B2T anticorps
  • BM600 anticorps
  • CSF anticorps
  • EBR2 anticorps
  • EBR2A anticorps
  • LAMB2T anticorps
  • LAMC2 anticorps
  • LAMNB2 anticorps

Protein level used designations for Laminin, gamma 2 (LAMC2) Kits ELISA

laminin 5 gamma 2 subunit , laminin subunit gamma-2 , laminin-5 gamma 2 , laminin, gamma 2 , laminin, gamma 2-like , laminin 5 gamma 2 , BM600-100kDa , CSF 140 kDa subunit , cell-scattering factor 140 kDa subunit , epiligrin subunit gamma , kalinin subunit gamma , ladsin 140 kDa subunit , laminin B2t chain , large adhesive scatter factor 140 kDa subunit , nicein subunit gamma , kalinin/nicein/epiligrin 100 kDa subunit , laminin gamma2 chain , laminin-5 subunit gamma , nicein, 100kD , nicein, 100kDa , lamimin, gamma 2

408043 Gallus gallus
442939 Canis lupus familiaris
457571 Pan troglodytes
511043 Bos taurus
715212 Macaca mulatta
100216328 Ovis aries
3918 Homo sapiens
16782 Mus musculus
791245 Equus caballus
192362 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour LAMC2 (LAMC2) Kits ELISA
Avez-vous cherché autre chose?