anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) Anticorps

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008].. De plus, nous expédions MARCH5 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MARCH5 54708 Q9NX47
MARCH5 69104 Q3KNM2
MARCH5 294079  
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Top anti-MARCH5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 59 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  MARCH5  Sample Type:  U937 Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of MARCH5 Antibody (N-term) (ABIN651864) in mouse kidney tissue lysates (35 µg/lane).MARCH5 (arrow) was detected using the purified polyclonal antibody. MARCH5 Antibody (N-term) (ABIN651864) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Poulet Lapin Inconjugué IC, IF, WB Western blot analysis of 42068 expression in HepG2 (A), mouse brain (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF, ELISA Immunofluorescence analysis of A549 cells, using MARCH5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, IF   200 μL Connectez-vous pour afficher 16 Days
$221.38
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué ICC, IF, WB Western Blot: MARCH5 Antibody [NBP2-21583] - Sample (20 ug of whole cell lysate) A: HeLa B: HeLa membrane, 12% SDS PAGE gel, diluted at 1:1000. Immunocytochemistry/Immunofluorescence: MARCH5 Antibody [NBP2-21583] - Confocal immunofluorescence analysis of methanol-fixed HeLa, using 39145 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué WB Western Blot: MARCH5 Antibody [NBP1-59585] - COLO205 cells lysate, concentration 0.2-1 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails

MARCH5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-MARCH5 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal MARCH5 Primary Antibody pour WB - ABIN2774746 : Karbowski, Neutzner, Youle: The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. dans The Journal of cell biology 2007 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre MARCH5 partenaires d’interaction

Rainbow Trout (Oncorhynchus mykiss) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after Viral hemorrhagic septicemia virus infection.

Human Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. the results of this study identified MARCH5 as a candidate oncogene (Montrer RAB1A Anticorps) in ovarian cancer and a potential target for ovarian cancer therapy.

  2. MARCH5 directly interacts with FUNDC1 (Montrer FUNDC1 Anticorps) to mediate its ubiquitylation at lysine 119 for subsequent degradation.

  3. These findings and data showing MARCH5-dependent degradation of MiD49 (Montrer SMCR7 Anticorps) upon stress support the possibility that MARCH5 regulation of MiD49 (Montrer SMCR7 Anticorps) is a novel mechanism controlling mitochondrial fission and, consequently, the cellular response to stress.

  4. Self-clearance mechanism of mitochondrial ligase MARCH5 contributes to mitochondria quality control.MARCH5 is regulated by auto-ubiquitination.

  5. MARCH5 binds MAVS (Montrer MAVS Anticorps) only during viral stimulation when MAVS (Montrer MAVS Anticorps) forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS (Montrer MAVS Anticorps).

  6. Our results indicate that HDAC6 (Montrer HDAC6 Anticorps) is a critical regulator of MFN2 (Montrer MFN2 Anticorps) degradation by MARCH5, thus protecting mitochondrial connectivity from hypoxic stress.

  7. A fine balance of Mfn1 (Montrer MFN1 Anticorps) levels is maintained by MARCH5-mediated quality control on acetylated Mfn1 (Montrer MFN1 Anticorps).

  8. MITOL regulates ER tethering to mitochondria by activating Mfn2 (Montrer MFN2 Anticorps) via K192 ubiquitination.

  9. balance between LC1 (Montrer MAP1B Anticorps) activation by S-nitrosylation and down-regulation by MITOL is critical for neuronal cell survival

  10. MARCH5 is an authentic E3 ubiquitin ligase (Montrer MUL1 Anticorps) and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 (Montrer TLR7 Anticorps) signaling via releasing the inhibitory action of TANK toward TRAF6 (Montrer TRAF6 Anticorps).

Mouse (Murine) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) interaction partners

  1. These findings suggest that MITOL plays a protective role against apoptosis in cardiomyocytes.

  2. MARCH5 binds MAVS (Montrer MAVS Anticorps) only during viral stimulation when MAVS (Montrer MAVS Anticorps) forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS (Montrer MAVS Anticorps).

  3. March5 is involved in maintaining mouse-ESC (mESC) pluripotency via catalysis of Prkar1a (Montrer PRKAR1A Anticorps) polyubiquitination and inhibition of the Raf (Montrer RAF1 Anticorps)/MEK (Montrer MDK Anticorps)/ERK (Montrer EPHB2 Anticorps) pathway.

  4. A fine balance of Mfn1 (Montrer MFN1 Anticorps) levels is maintained by MARCH5-mediated quality control on acetylated Mfn1 (Montrer MFN1 Anticorps).

  5. MARCH5 is an authentic E3 ubiquitin ligase (Montrer MUL1 Anticorps) and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 (Montrer TLR7 Anticorps) signaling via releasing the inhibitory action of TANK toward TRAF6 (Montrer TRAF6 Anticorps).

  6. Results indicate that MITOL plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway.

MARCH5 profil antigène

Profil protéine

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006

Gene names and symbols associated with MARCH5

  • membrane-associated ring finger (C3HC4) 5 (march5) anticorps
  • membrane associated ring-CH-type finger 5 (MARCH5) anticorps
  • membrane associated ring-CH-type finger 5 (march5) anticorps
  • membrane associated ring-CH-type finger 5 L homeolog (march5.L) anticorps
  • membrane-associated ring finger (C3HC4) 5 (March5) anticorps
  • membrane associated ring-CH-type finger 5 (March5) anticorps
  • 1810015H18Rik anticorps
  • 2310008I22Rik anticorps
  • 2700055A20Rik anticorps
  • 5730499H23Rik anticorps
  • E130202O05Rik anticorps
  • Mar-05 anticorps
  • MARCH-V anticorps
  • MARCH5 anticorps
  • Marchv anticorps
  • MITOL anticorps
  • Rnf153 anticorps
  • zgc:162966 anticorps

Protein level used designations for MARCH5

membrane-associated ring finger (C3HC4) 5 , E3 ubiquitin-protein ligase MARCH5 , MARCH-V , membrane-associated RING finger protein 5 , membrane-associated RING-CH protein V , mitochondrial ubiquitin ligase , ring finger protein 153

GENE ID SPECIES
100302643 Oncorhynchus mykiss
450607 Pan troglodytes
698517 Macaca mulatta
100144728 Xenopus (Silurana) tropicalis
100157340 Sus scrofa
100341637 Oryctolagus cuniculus
561952 Danio rerio
444564 Xenopus laevis
423815 Gallus gallus
54708 Homo sapiens
612766 Canis lupus familiaris
540937 Bos taurus
69104 Mus musculus
294079 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-MARCH5 (MARCH5) Anticorps
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