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anti-NPC1 Anticorps

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

49 Résultats:

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (AA 34-174) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain IHC, ELISA, WB Hôte: Souris Monoclonal 8D10B6 unconjugated
Pubmed 2
N° du produit ABIN1724876
$448.80
Plus shipping costs $45.00
0.1 mg
local_shipping Destination: Etats-Unis
Envoi sous 3 à 4 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (AA 34-174) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain FACS, IHC, ELISA, WB Hôte: Souris Monoclonal unconjugated
N° du produit ABIN1845969
$478.68
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (AA 591-620) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain IF, IHC, ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031998
$493.63
Plus shipping costs $45.00
0.4 mL (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 2 à 3 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain ELISA, FM, IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6655360
$379.00
Plus frais de port $45.00 et $24.00 pour carboglace
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (AA 591-620) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain IF, IHC (p), WB Hôte: Lapin Polyclonal RB33297 unconjugated
N° du produit ABIN657395
$412.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 10 à 11 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (AA 151-250) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain ELISA, WB Hôte: Souris Monoclonal 4H2 unconjugated
N° du produit ABIN562034
$600.00
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 12 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain IF, IHC, IHC (p), IP, WB Hôte: Souris Monoclonal unconjugated
N° du produit ABIN462125
$727.83
Plus shipping costs $45.00
50 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 14 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain EIA, IHC (p), WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500383
$511.50
Plus shipping costs $45.00
0.1 mg
local_shipping Destination: Etats-Unis
Envoi sous 6 à 8 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 IEM, IF, IHC, IP, WB Hôte: Lapin Polyclonal unconjugated
Pubmed 3
N° du produit ABIN540364
$702.86
Plus shipping costs $45.00
100 μL
local_shipping Destination: Etats-Unis
Envoi sous 11 à 12 jours ouvrables

anti-NPC1 anticorps (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivité: Humain, Souris ELISA, IHC, IHC (p), WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN959667
$1,015.67
Plus shipping costs $45.00
50 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 14 jours ouvrables
  • Type Primary
    • Primary
  • Target Niemann-Pick Disease, Type C1 (NPC1)
    • Niemann-Pick Disease, Type C1 (NPC1)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4 Molecule (CD4)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Nuclear Factor-KB P65 (NFkBP65)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Integrin alpha M (ITGAM)
    • Interleukin 6 (IL6)
    • CD8
    • Histone H4
    • CD44
    • Jun Proto-Oncogene (JUN)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Myc Proto-Oncogene protein (MYC)
    • Catenin, beta
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Vimentin (VIM)
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD5 Molecule (CD5)
    • Interleukin 2 (IL2)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • CD3
    • Insulin Receptor Substrate 1 (IRS1)
    • CD34
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Keratin 18 (KRT18)
    • CD14
    • Synuclein, alpha (SNCA)
  • Application
    • ELISA
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Immunoprecipitation (IP)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Enzyme Immunoassay (EIA)
    • Fluorescence Microscopy (FM)
    • Immunoelectron Microscopy (IEM)
    • Immunofluorescence (Cultured Cells) (IF (cc))
  • Réactivité
    • Humain
    • Souris
    • Rat
  • Cité dans publications
  • Images disponible
  • Hote
    • Lapin
    • Chèvre
    • Souris
  • Clonalité
    • Polyclonal
    • Monoclonal
  • Clone
    • 1B12
    • 4H2
    • 8D10B6
    • RB33297
  • Epitope
    • Internal Region
    • Center
    • AA 590-620
    • AA 591-620
    • C-Term
    • AA 23-269
    • AA 34-174
    • AA 1022-1278
    • AA 151-250
    • AA 372-622
  • Conjugué
    • Inconjugué
    • Biotin
    • FITC
    • APC
    • Alkaline Phosphatase (AP)
    • HRP
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • Isotype
    • IgG
    • IgG1
    • Ig Fraction
    • IgG2a kappa
  • Format
    • Liquid
    • Lyophilized

NPC1 profil antigène

Profil protéine

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) anticorps
  • Niemann-Pick disease, type C1 (npc1) anticorps
  • Niemann-Pick C1 protein (LOC579887) anticorps
  • NPC intracellular cholesterol transporter 1 (Npc1) anticorps
  • A430089E03Rik anticorps
  • C85354 anticorps
  • Cdig2 anticorps
  • D18Ertd139e anticorps
  • D18Ertd723e anticorps
  • im:7149020 anticorps
  • lcsd anticorps
  • nmf164 anticorps
  • NPC anticorps
  • spm anticorps
  • wu:fb53a12 anticorps
  • wu:fc29a12 anticorps

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus

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