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DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. De plus, nous expédions DLK1 Protéines (20) et DLK1 Kits (12) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 181 products:
Human Monoclonal DLK1 Primary Antibody pour ICC, FACS - ABIN969086
Espina, Méndez-Vidal, Moreno-Mateos, Sáez, Romero-Franco, Japón, Pintor-Toro: Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation. dans Molecular biology of the cell 2009
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Human Monoclonal DLK1 Primary Antibody pour CyTOF, FACS - ABIN4899811
Kim, Lin, Zelterman, Yun: Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity. dans Cancer research 2009
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Human Monoclonal DLK1 Primary Antibody pour CyTOF, FACS - ABIN4899812
Chung, Lapoint, Martinez, Kennedy, Boysen Sandberg, McIntosh: Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes. dans Endocrinology 2006
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Human Polyclonal DLK1 Primary Antibody pour WB - ABIN522231
Kilian, Beck-Sickinger: Recombinant expression and characterization of biologically active protein delta homolog 1. dans Protein expression and purification 2015
Dog (Canine) Polyclonal DLK1 Primary Antibody pour WB - ABIN2773880
Zhou, Wang, Wang, Zhu, Shu, Liao, Yu, Gao, Xi, Wang, Zhang, Yuan, Jiang: Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. dans Meat science 2010
Mouse (Murine) Monoclonal DLK1 Primary Antibody pour ELISA, WB - ABIN1169190
Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche. dans Stem cells (Dayton, Ohio) 2009
Human Monoclonal DLK1 Primary Antibody pour FACS, IHC - ABIN1169184
Kluth, Radke, Kögler: Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1. dans Stem cells international 2013
DLK1 mRNA expression in mesenteric fat was higher than subcutaneous fat. DLK1 mRNA expression in Holstein cattle mesenteric fat was higher than Wagyu cattle.
The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed.
tissue-specific expression patterns of Dlk-1 splice variants in bovine tissues
The expression of piRNAs encoded at DLK1-DIO3 (Montrer DIO3 Anticorps) enhances the prognostic potential of small non-coding RNAs specific to this locus in predicting lung cancer patient outcome.
targeting DLK1 might inhibit the tumor growth via initiating cell differentiation of hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)) cancer stem cell.
SASH1 (Montrer SASH1 Anticorps) acts through NOTCH1 (Montrer NOTCH1 Anticorps) and its inhibitor DLK1 in a three-dimensional model of lumenogenesis involving CEACAM1 (Montrer CEACAM1 Anticorps).
The data presented in this work suggest that a fine regulation of NOTCH (Montrer NOTCH1 Anticorps) signaling BY DLK1 plays an important role in the control of breast cancer cell proliferation and invasion.
results demonstrate that miR (Montrer MLXIP Anticorps)-129-5p inhibits non-small cell lung cancer stemness and chemoresistance through direct targeting of DLK1
A complex defect of DLK1 ( approximately 14-kb deletion and 269-bp duplication) was identified in a family with central precocious puberty. This deletion included the 5' untranslated region and the first exon of DLK1, including the translational start site. Only family members who inherited the defect from their father have precocious puberty, consistent with the known imprinting of DLK1.
Loss of DLK1 expression is associated with fetal growth retardation complications of pregnancy.
In neonatal skin, DLK1 exhibited a high degree of monoallelic expression from the paternal allele.
The study evaluated the roles of extracellular soluble DLK1, comprising six EGF (Montrer EGF Anticorps)-like domains and juxtamembrane regions, in human pancreatic cancer MIA (Montrer MIA Anticorps) PaCa-2 cells in vitro and in vivo. Soluble DLK1 exerted antitumor effects not only in cancer cell migration and anchorage-independent cell growth but also in in vivo tumor growth.
Treatment of mice with recombinant human DLK1 during pregnancy has significant effects on AT of the offspring. This can be associated with counter-regulatory changes in the Notch1 (Montrer NOTCH1 Anticorps) signaling cascade.
trans-associations occur between three imprinted genes IGF2, DLK1 and MEG3 both in fetal liver and muscle cells.
We did not observe significantly different expression of DLK1, MEG3 or PEG11 (Montrer RTL1 Anticorps) mRNA in any of analyzed breeds.
QUASEP supports paternal expression of DLK1 in whole brain, carcass, liver and placental tissues of day 30 interbreed porcine fetuses.
the sequence of porcine DLK1 (pDLK1)was examined,the expression and alternative splicing isoforms in the pig (Sus scrofa) was compared with human
Polymorphisms, imprinting status and quantitative trait locus analyses of the porcine DLK1 and MEG3 genes i swine.
Expression of DLK1 splice variants during adipocyte development in vitro and in vivo.
This study suggests that Pref-1 is an endocrine factor which is synergistically increased by obesity and age.
Gene body methylation of noncoding RNA genes was observed and among these microRNA genes were prominent. Of particular note, observed only in hyperphenylalaninemic animals, was hypomethylation of miRNA genes within the imprinted Dlk1-Dio3 (Montrer DIO3 Anticorps) locus on chromosome 12.
The role of elevated oxygen levels in eroding imprinted Dlk1 expression during prolonged culture and in vitro differentiation.
Pref-1 mRNA is a novel substrate of RNase-L (Montrer RNASEL Anticorps).
the conserved sequences in IG-DMR (Montrer WDR20 Anticorps) are involved in the expression regulation of some of the imprinted genes in the Dlk1-Dio3 (Montrer DIO3 Anticorps) domain
To investigate the nature of these more variably methylated secondary differentially methylated regions, we adopted a hairpin linker bisulfite mutagenesis approach to examine CpG dyad methylation at differentially methylated regions associated with the murine Dlk1/Gtl2 imprinting cluster on both complementary strands.
NOTCH1 (Montrer NOTCH1 Anticorps) ligand Delta-like 1 (Montrer DLL1 Anticorps) homolog (DLK1) self interacts
the salivary gland phenotype of Dlk1 knock-out mice, was investigated.
The brain-specific (Montrer CALY Anticorps) miR (Montrer MLXIP Anticorps)-379/miR (Montrer MLXIP Anticorps)-410 gene cluster at the imprinted Dlk1-Dio3 (Montrer DIO3 Anticorps) domain is implicated in several aspects of brain development and function.
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
, preadipocyte factor-1
, protein delta homolog 1
, delta-like 1 homolog (Drosophila)
, delta-like protein 1
, protein delta homolog 1-like
, fetal antigen 1
, preadipocyte factor 1
, adipocyte differentiation inhibitor protein
, stromal cell derived protein 1