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CD11b anticorps

ITGAM Reactivité: Humain FACS, Func Hôte: Souris Monoclonal ICRF44 unconjugated
N° du produit ABIN1176910
  • Antigène Voir toutes CD11b (ITGAM) Anticorps
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivité
    • 274
    • 173
    • 68
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 4
    • 4
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    • 2
    • 1
    Humain
    Hôte
    • 152
    • 113
    • 104
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 274
    • 96
    • 1
    Monoclonal
    Conjugué
    • 117
    • 37
    • 32
    • 28
    • 22
    • 11
    • 8
    • 8
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    • 6
    • 6
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    • 3
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    • 3
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    • 2
    • 2
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    • 2
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    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD11b est non-conjugé
    Application
    • 276
    • 87
    • 83
    • 82
    • 58
    • 43
    • 38
    • 22
    • 20
    • 20
    • 13
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    Flow Cytometry (FACS), Functional Studies (Func)
    Marque
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Immunogène
    Human monocytes
    Clone
    ICRF44
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGAM Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Agent conservateur
    Azide free
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Antigène
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Autre désignation
    CD11b/Mac-1 (ITGAM Produits)
    Synonymes
    anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
    Sujet
    The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin beta2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
    Synonyms: Mac-1alpha, integrin alphaM subunit, CR3 alpha chain
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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