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CD3 epsilon anticorps (FITC)

CD3E Reactivité: Souris FACS Hôte: Hamster Monoclonal FITC

N° du produit ABIN133682

Fiche de données

Antigène Voir toutes CD3 epsilon (CD3E) Anticorps

CD3 epsilon (CD3E)
Reactivité
202

148

44

37

18

8

8

8

7

4

4

4

4

3

3

3

3

3

3

1

1

1

1

1
Souris
Hôte
123

105

36

24

16

10

1

1
Hamster
Clonalité
206

104

6
Monoclonal
Conjugué
120

29

27

18

14

6

6

6

5

4

4

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD3 epsilon est conjugé à/à la FITC
Application
232

135

85

83

67

66

32

27

22

17

14

13

13

13

8

6

4

4

3

3

3

3

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Specificité

Mouse CD3

Immunogène

H-2Kb sp . Fusion Partner: Murine myeloma cell line SP2/0 . Donor: BALB/c

Isotype

IgG

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CD3E Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (C-Term) antibody
CD3E Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 25-207) antibody
CD3E Reactivité: Humain WB, IHC, IP Hôte: Lapin Polyclonal unconjugated

anti-CD3 epsilon (CD3E) (AA 28-185) antibody
CD3E Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

Restrictions

For Research Use only
Concentration

1µg/10 cells

Stock

4 °C
Antigène

CD3 epsilon (CD3E)

Autre désignation

CD3e (CD3E Produits)

Synonymes

anticorps cd3e, anticorps CD3E, anticorps t3e, anticorps tcre, anticorps AI504783, anticorps CD3, anticorps CD3epsilon, anticorps T3e, anticorps T3E, anticorps TCRE, anticorps CD3e molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps cd3e, anticorps CD3E, anticorps Cd3e

Sujet

Anti-mouse T3 complex CD3 monoclonal antibody is specific for a 25 kDa protein component ( -T3) of the antigen specific T cell receptor on all mouse strains tested. The -T3 protein has been shown to be non-covalently associated with the cell surface heterodimer of the CD3 associated complex. This monoclonal antibody reacts with all mature T cells and can both activate and inhibit T cell function (1). This fact identifies -T3 as a cell surface protein involved in the transduction of activation signals. All peripheral T cells express this determinant, however, B cells and bone marrow cells have proven to be negative. Although the expression of this particular epitope on peripheral T cells is uniformly high, staining of thymocytes reveals distinct subpopulations of cells differing in the level of expression of this marker. This antibody will prove useful in studying the role of various components of the TCR complex in T cell activation and development, and will allow for the development of an animal model in which to investigate the immunoregulatory effects of in vivo administration of anti-CD3 antibodies, an area of obvious clinical

Pathways

TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway