PDK2 anticorps (AA 128-407)

N° du produit ABIN1681304

Détail du produit anti-PDK2 anticorps

Antigène: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Épitope: AA 128-407

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: PTMAQGVLEY KDTYGDDPVS NQNIQYFLDR FYLSRISIRM LINQHTLIFD GSTNPAHPKH IGSIDPNCNV SEVVKDAYDM AKLLCDKYYM ASPDLEIQEI NAANSKQPIH MVYVPSHLYH MLFELFKNAM RATVESHESS LILPPIKVMV ALGEEDLSIK MSDRGGGVPL RKIERLFSYM YSTAPTPQPG TGGTPLAGFG YGLPISRLYA KYFQGDLQLF SMEGFGTDAV IYLKALSTDS VERLPVYNKS AWRHYQTIQE AGDWCVPSTE PKNTSTYRVS

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDK2

Antigène: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Autre désignation: PDK2 (PDK2 Produits)

Synonymes: anticorps PDHK2, anticorps PDKII, anticorps Pdk, anticorps zgc:56209, anticorps PDK2, anticorps pyruvate dehydrogenase kinase 2, anticorps pyruvate dehydrogenase kinase, isoenzyme 2, anticorps pyruvate dehydrogenase kinase, isozyme 2b, anticorps PDK2, anticorps Pdk2, anticorps pdk2b

Sujet: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,PDK2,PDHK2,PDKII,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK2

Poids moléculaire: 38 kDa/46 kDa

ID gène: 5164

UniProt: Q15119

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg