p300 anticorps (AA 1572-2371)
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- Antigène Voir toutes p300 (EP300) Anticorps
- p300 (EP300) (E1A Binding Protein P300 (EP300))
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Épitope
- AA 1572-2371
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Reactivité
- Humain, Souris, Rat, Singe, Vison
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp p300 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Reacts with human p300 protein (residues 1868-1921)
- Réactivité croisée
- Souris
- Réactivité croisée (Details)
- Cross reacts with proteins from mouse, rat, monkey and mink.
- Purification
- Purified (protein A)
- Immunogène
- Fusion protein containing residues 1572-2371 of human p300
- Clone
- RW128
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product EP300 Anticorps primaire
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- Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF1:10-1:2000, IP1:10-1:500, WB1:250-1:500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4, Sodium azide 0.1 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Antigène
- p300 (EP300) (E1A Binding Protein P300 (EP300))
- Autre désignation
- p300 (EP300 Produits)
- Synonymes
- anticorps KAT3B, anticorps RSTS2, anticorps p300, anticorps A430090G16, anticorps A730011L11, anticorps p300 HAT, anticorps E1A binding protein p300, anticorps histone acetyltransferase p300, anticorps EP300, anticorps LOC446056, anticorps ep300, anticorps Ep300
- Sujet
- Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability.
- ID gène
- 2033
- UniProt
- Q09472
- Pathways
- Signalisation p53, Signalisation Notch, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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