SARM1 anticorps (C-Term)

N° du produit ABIN1887395

Détail du produit anti-SARM1 anticorps

Antigène: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SARM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Ion exchange chromatography purified

Immunogène: Peptide corresponding to amino acids near the C-terminus of human SARM.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur SARM1

Antigène: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Autre désignation: SARM (SARM1 Produits)

Synonymes: anticorps A830091I15Rik, anticorps C78606, anticorps MyD885, anticorps Sarm, anticorps MyD88-5, anticorps SAMD2, anticorps SARM, anticorps sterile alpha and TIR motif containing 1, anticorps sterile alpha and HEAT/Armadillo motif containing 1, anticorps SARM1, anticorps Sarm1, anticorps sarm1

Sujet: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense.While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

NCBI Accession: NP_055892

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades