TCF7L1 anticorps

N° du produit ABIN2459996

Détail du produit anti-TCF7L1 anticorps

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7L1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF7L1.

Information d'application

Indications d'application: TCF7L1 antibody can be used for detection of TCF7L1 by ELISA at 1:1562500. TCF7L1 antibody can be used for detection of TCF7L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TCF7L1 antibody at -20 °C.

Détails sur TCF7L1

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Autre désignation: TCF7L1 (TCF7L1 Produits)

Synonymes: anticorps TCF-3, anticorps TCF3, anticorps Tcf-3, anticorps Tcf3, anticorps bHLHb21, anticorps tcf3c, anticorps tcf3d, anticorps xtcf3, anticorps XTCF-3, anticorps tcf7l1, anticorps tcf3b, anticorps TCF-3-A, anticorps tcf-3, anticorps tcf3, anticorps tcf3a, anticorps zTcf-3, anticorps transcription factor 7 like 1, anticorps transcription factor 7 like 1 (T cell specific, HMG box), anticorps transcription factor 7 like 1 L homeolog, anticorps transcription factor 7 like 1 S homeolog, anticorps transcription factor 7 like 1b, anticorps transcription factor 7 like 1a, anticorps TCF7L1, anticorps Tcf7l1, anticorps tcf7l1.L, anticorps tcf7l1.S, anticorps tcf7l1b, anticorps tcf7l1a

Sujet: TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.

Poids moléculaire: 63 kDa

ID gène: 83439

NCBI Accession: NP_112573

UniProt: Q9HCS4

Pathways: Signalisation WNT, Stem Cell Maintenance