NR3C2 anticorps

N° du produit ABIN2462859

Détail du produit anti-NR3C2 anticorps

Antigène: NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR3C2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR3C2.

Information d'application

Indications d'application: NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR3C2 antibody at -20 °C.

Détails sur NR3C2

Antigène: NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))

Autre désignation: NR3C2 (NR3C2 Produits)

Synonymes: anticorps mr, anticorps si:ch211-189l17.1, anticorps LOC100302443, anticorps NR3C2, anticorps LOC443144, anticorps MLR, anticorps MR, anticorps MCR, anticorps NR3C2VIT, anticorps Mlr, anticorps mlr, anticorps nuclear receptor subfamily 3, group C, member 2, anticorps nuclear receptor subfamily 3 group C member 2, anticorps mineralocorticoid receptor, anticorps nuclear receptor subfamily 3 group C member 2 L homeolog, anticorps nr3c2, anticorps NR3C2, anticorps LOC443144, anticorps Nr3c2, anticorps nr3c2.L

Sujet: NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

Poids moléculaire: 107 kDa

ID gène: 4306

NCBI Accession: NP_000892

UniProt: P08235

Pathways: ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway