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BCL10 anticorps
BCL10
Reactivité: Humain
WB, IHC, ELISA
Hôte: Souris
Monoclonal
4F8E8H8
unconjugated
N° du produit ABIN2464015
Détail du produit anti-BCL10 anticorps
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Antigène
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BCL10
(B-Cell CLL/lymphoma 10 (BCL10))
Reactivité
Toutes les réactivités sur BCL10 Anticorps
Humain
Hôte
Toutes les hôtes sur BCL10 Anticorps
Souris
Clonalité
Toutes les clonalités sur BCL10 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers BCL10 Anticorps
Cet anticorp BCL10 est non-conjugé
Application
Tous les applications à travers BCL10 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Purification
Antibody is purified by protein A affinity chromatography.
Immunogène
Ni-NTA purified recombinant human BCL-10 expressed in E. Coli strain BL21 (DE3).
Clone
4F8E8H8
Isotype
IgG1
Top Product
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Alternatives
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Information d'application
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Indications d'application
IHC(P):Dilution 1:1,000 - 1:2,000 IHC(F):Dilution 1:1,000 - 1:2,000 Western blot:Dilution 1:2,000 - 1:5,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Stockage
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Conseil sur la manipulation
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Stock
-20 °C
Stockage commentaire
BCL-10 monoclonal antibody can be stored at -20 °C, stable for one year.
Détails sur BCL10
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Antigène
BCL10
(B-Cell CLL/lymphoma 10 (BCL10))
Autre désignation
BCL10 (BCL10 Produits )
Synonymes
anticorps CARMEN, anticorps CIPER, anticorps CLAP, anticorps c-E10, anticorps mE10, anticorps BCL10, anticorps AI132454, anticorps BCL-10, anticorps C81403, anticorps ME10, anticorps cE10, anticorps bcl10, anticorps B-cell CLL/lymphoma 10, anticorps B-cell lymphoma/leukemia 10-like, anticorps B cell leukemia/lymphoma 10, anticorps B-cell lymphoma/leukemia 10, anticorps BCL10, anticorps Bcl10, anticorps bcl10, anticorps LOC100223183
Sujet
B-cell CLL/lymphoma 10, also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-κ,B. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-κ,B signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-κ,B, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
ID gène
8915
UniProt
O95999
Pathways
TCR Signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Tube Formation , Positive Regulation of Endopeptidase Activity , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
Vus récemment
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