CD11c anticorps (Internal Region)

N° du produit ABIN2469521

Détail du produit anti-CD11c anticorps

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Épitope: Internal Region

Reactivité: Humain, Gorilla

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD11c est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TDO2 (57 % ).

Purification: Immunoaffinity Chromatography

Immunogène: Integrin alpha X antibody was raised against a peptide located near the internal domain of Integrin alpha X (Human).

Information d'application

Indications d'application: Integrin alpha X antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: Integrin alpha X antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur CD11c

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Autre désignation: Integrin alpha X (ITGAX Produits)

Synonymes: anticorps CD11C, anticorps SLEB6, anticorps RGD1561123, anticorps AI449405, anticorps Cd11c, anticorps Cr4, anticorps N418, anticorps integrin subunit alpha X, anticorps integrin alpha X, anticorps ITGAX, anticorps Itgax

Sujet: ITGAX encodes the integrin alpha X chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 seems to broadly overlap the properties of the alpha M beta 2 integrin in adherence of neutrophils and monocytes to stimulated endothelium, and the phagocytosis of complement coated particles.

ID gène: 3687

UniProt: P20702

Pathways: Système du Complément, Activated T Cell Proliferation, Integrin Complex