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CD3 epsilon anticorps

CD3E Reactivité: Souris FACS, WB, IHC, IF, IP, Func Hôte: Hamster Monoclonal 145-2C11 unconjugated
N° du produit ABIN2567596
  • Antigène Voir toutes CD3 epsilon (CD3E) Anticorps
    CD3 epsilon (CD3E)
    Reactivité
    • 202
    • 167
    • 44
    • 41
    • 18
    • 8
    • 8
    • 8
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    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 142
    • 105
    • 36
    • 24
    • 16
    • 10
    • 1
    • 1
    Hamster
    Clonalité
    • 206
    • 123
    • 6
    Monoclonal
    Conjugué
    • 120
    • 30
    • 28
    • 19
    • 14
    • 7
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    • 6
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD3 epsilon est non-conjugé
    Application
    • 232
    • 154
    • 85
    • 83
    • 69
    • 66
    • 32
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    • 19
    • 14
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)
    Specificité
    The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    145-2C11
    Isotype
    IgG
    Top Product
    Discover our top product CD3E Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.5 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Stock
    4 °C
    Stockage commentaire
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Antigène
    CD3 epsilon (CD3E)
    Autre désignation
    CD3e (CD3E Produits)
    Synonymes
    anticorps cd3e, anticorps CD3E, anticorps t3e, anticorps tcre, anticorps AI504783, anticorps CD3, anticorps CD3epsilon, anticorps T3e, anticorps T3E, anticorps TCRE, anticorps CD3e molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps cd3e, anticorps CD3E, anticorps Cd3e
    Sujet
    The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
    ID gène
    12501
    UniProt
    P22646
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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