EPOR anticorps (pTyr368)
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- Antigène Voir toutes EPOR Anticorps
- EPOR (Erythropoietin Receptor (EPOR))
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Épitope
- pTyr368
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EPOR est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- The antibody detects endogenous level of Epo-R only when phosphorylated at tyrosine 368.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- Epo-R (phospho Tyr368) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y (p)-L-V) derived from Human Epo-R.
- Isotype
- IgG
- Top Product
- Discover our top product EPOR Anticorps primaire
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- Indications d'application
- Western Blot: 1:500~1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Antigène
- EPOR (Erythropoietin Receptor (EPOR))
- Autre désignation
- Epo-R (EPOR Produits)
- Synonymes
- anticorps EPOR, anticorps epor, anticorps EPO-R, anticorps erythropoietin receptor, anticorps erythropoietin receptor L homeolog, anticorps EPOR, anticorps epor, anticorps Epor, anticorps epor.L
- Sujet
- Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
- Poids moléculaire
- 55 kDa
- ID gène
- 2057
- NCBI Accession
- NP_000112
- UniProt
- P19235
- Pathways
- Signalistation JAK/STAT
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