HIF1A anticorps (AA 329-530)

N° du produit ABIN2667743

Détail du produit anti-HIF1A anticorps

Antigène: HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))

Épitope: AA 329-530

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HIF1A est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Protein A Chromatography

Immunogène: This HIF-1 alpha antibody was raised against a partial protein containing amino acid residues 329-530 of human HIF-1 alpha.

Clone: ESEE122

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -20 °C

Stockage commentaire: Antibodies in solution can be stored at -20 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-HIF1A (ABIN2667743)

Edalat, Stegen, Klumpp, Haehl, Schilbach, Lukowski, Kühnle, Bernhardt, Buschauer, Zips, Ruth, Huber: "BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells." dans: Oncotarget, Vol. 7, Issue 12, pp. 14259-78, (2016) (PubMed).

Tan, Campo, Han, Turley, Pezzella, Gatter, Harris, Fox: "Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer." dans: Breast cancer research : BCR, Vol. 9, Issue 6, pp. R89, (2008) (PubMed).

Yoshimura, Dhar, Kohno, Kubota, Fujii, Ueda, Kinugasa, Tachibana, Nagasue: "Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 24, pp. 8554-60, (2004) (PubMed).

Beasley, Leek, Alam, Turley, Cox, Gatter, Millard, Fuggle, Harris: "Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients." dans: Cancer research, Vol. 62, Issue 9, pp. 2493-7, (2002) (PubMed).

Chen, Smit-McBride, Lewis, Sharif, Privalsky: "Nuclear hormone receptors involved in neoplasia: erb A exhibits a novel DNA sequence specificity determined by amino acids outside of the zinc-finger domain." dans: Molecular and cellular biology, Vol. 13, Issue 4, pp. 2366-76, (1993) (PubMed).

Détails sur HIF1A

Antigène: HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))

Autre désignation: HIF-1 alpha (HIF1A Produits)

Synonymes: anticorps hif1a, anticorps AA959795, anticorps HIF1alpha, anticorps MOP1, anticorps bHLHe78, anticorps HIF-1A, anticorps HIF-1alpha, anticorps HIF1, anticorps HIF1-ALPHA, anticorps PASD8, anticorps HIF1-alpha, anticorps hif-1a, anticorps hypoxia inducible factor 1 alpha, anticorps hypoxia inducible factor 1, alpha subunit, anticorps hypoxia inducible factor 1 alpha subunit, anticorps HIF (Hypoxia Inducible Factor) homologa, anticorps hif-1a, anticorps Hif1a, anticorps HIF1A, anticorps hif1a, anticorps hif-1

Poids moléculaire: 100 kDa

ID gène: 3091

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, L'effet Warburg