RHOA anticorps

N° du produit ABIN272117

Détail du produit anti-RHOA anticorps

Antigène: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Rho A protein. (region surrounding Arg182)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur RHOA

Antigène: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Autre désignation: RhoA (RHOA Produits)

Synonymes: anticorps ARH12, anticorps ARHA, anticorps RHO12, anticorps RHOH12, anticorps Arha, anticorps Arha1, anticorps Arha2, anticorps arha, anticorps arha2, anticorps xrhoa, anticorps arh12, anticorps rho12, anticorps rhoh12, anticorps rhoa, anticorps RHO1, anticorps Rhoa, anticorps wu:fa66g04, anticorps wu:fb26g07, anticorps zgc:66058, anticorps zgc:85805, anticorps ARHC, anticorps rhoae, anticorps zgc:64015, anticorps ras homolog family member A, anticorps ras homolog family member A S homeolog, anticorps ras homolog family member A L homeolog, anticorps ras homolog gene family, member Aa, anticorps ras homolog family member Ca, anticorps RHOA, anticorps Rhoa, anticorps rhoa.S, anticorps rhoa, anticorps rhoa.L, anticorps rhoaa, anticorps rhoca

Sujet: The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1 (A and B), Rap 2, R-Ras and Ral (A and B), exhibit approximately 50 % amino acid homology to Ras. The three mammalian Rho proteins (A, B and C) are approximately 30 % homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy terminal CAAX sequence (C, cysteine, A, aliphatic amino acid, X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.Synonyms: ARH12, ARHA, RHO12, Rho cDNA clone 12, Transforming protein RhoA

Poids moléculaire: approx. 22 kDa

ID gène: 387

NCBI Accession: NP_001655

UniProt: P61586

Pathways: Dynamique des Microtubules, Signalisation WNT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome